CRCGN014_HEPG2_24H:C16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description trans-cinnamaldehyde 40.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN014_HEPG2_24H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 6.13087
CIAO3 cytosolic iron-sulfur assembly component 3 5.35903
TATDN2 TatD DNase domain containing 2 3.99879
TIAM1 T-cell lymphoma invasion and metastasis 1 3.7177
UBQLN2 ubiquilin 2 3.65619
ADRB2 adrenoceptor beta 2, surface 3.43666
ZNF589 zinc finger protein 589 3.26251
LOC122526780 uncharacterized LOC122526780 3.08528
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.08007
LCN2 lipocalin 2 3.04547
C2CD2 C2 calcium-dependent domain containing 2 2.80469
NOTCH1 notch 1 2.68954
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.68686
RPP38 ribonuclease P/MRP 38kDa subunit 2.52947
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.44383
GARRE1 granule associated Rac and RHOG effector 1 2.41528
KIF20A kinesin family member 20A 2.35877
PKN1 protein kinase N1 2.33327
STIMATE STIM activating enhancer 2.20758
NPDC1 neural proliferation, differentiation and control, 1 2.19275
SATB1 SATB homeobox 1 2.14006
KDM5D lysine (K)-specific demethylase 5D 2.12457
SFTPB surfactant protein B 2.07463

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -7.27429
GOLT1B golgi transport 1B -4.90512
HAT1 histone acetyltransferase 1 -4.8009
CD320 CD320 molecule -4.4413
SLC35F2 solute carrier family 35, member F2 -3.5846
TM9SF3 transmembrane 9 superfamily member 3 -3.46647
ZNF586 zinc finger protein 586 -3.13624
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.9892
CTNND1 catenin (cadherin-associated protein), delta 1 -2.77781
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.69467
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.21471