CRCGN014_HEPG2_24H:C18 Gene Set
Genes
24 genes differentially expressed following the CRCGN014_HEPG2_24H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MOK
|
MOK protein kinase
|
4.477
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.16408
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.04645
|
|
UBQLN2
|
ubiquilin 2
|
3.64019
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.4705
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.3763
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.10598
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.91914
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.89087
|
|
CCNF
|
cyclin F
|
2.69211
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.63732
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.54024
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.27489
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.23186
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.13687
|
|
STXBP2
|
syntaxin binding protein 2
|
2.06062
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-4.96229
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.09585
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.86027
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.42159
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.2084
|
|
LDHD
|
lactate dehydrogenase D
|
-2.79506
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.33244
|
|
CCNB2
|
cyclin B2
|
-2.08104
|