CRCGN014_HEPG2_24H:C19 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_24H:C19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
4.64155
|
|
EGF
|
epidermal growth factor
|
4.5139
|
|
MYLK
|
myosin light chain kinase
|
4.21354
|
|
PLSCR3
|
phospholipid scramblase 3
|
3.81911
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.33743
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.04369
|
|
CHN1
|
chimerin 1
|
2.87275
|
|
SFTPB
|
surfactant protein B
|
2.72294
|
|
GPATCH8
|
G patch domain containing 8
|
2.66721
|
|
THADA
|
thyroid adenoma associated
|
2.63533
|
|
MBIP
|
MAP3K12 binding inhibitory protein 1
|
2.49491
|
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
2.33868
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.32239
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.29799
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.29405
|
|
JADE2
|
jade family PHD finger 2
|
2.24347
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
2.2414
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.2298
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.22482
|
|
NENF
|
neudesin neurotrophic factor
|
2.17749
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.16009
|
|
RPA3
|
replication protein A3, 14kDa
|
2.10699
|
|
GATA2
|
GATA binding protein 2
|
2.01756
|
|
TAF1B
|
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
|
2.01315
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.3844
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-8.30742
|
|
LDHD
|
lactate dehydrogenase D
|
-7.72602
|
|
TCERG1
|
transcription elongation regulator 1
|
-4.22676
|
|
CCNB2
|
cyclin B2
|
-4.02221
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.84603
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.82819
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.72901
|
|
ZNF586
|
zinc finger protein 586
|
-3.71479
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.23906
|
|
CD320
|
CD320 molecule
|
-3.1968
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.13323
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-3.11928
|
|
GNAS
|
GNAS complex locus
|
-3.07233
|
|
DDHD2
|
DDHD domain containing 2
|
-2.60412
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.5969
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.56191
|
