CRCGN014_HEPG2_24H:C20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description iq 38.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

42 genes differentially expressed following the CRCGN014_HEPG2_24H:C20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STK10 serine/threonine kinase 10 4.93463
STIMATE STIM activating enhancer 3.98371
GPER1 G protein-coupled estrogen receptor 1 3.7215
JADE2 jade family PHD finger 2 3.63239
ADRB2 adrenoceptor beta 2, surface 3.47613
E2F2 E2F transcription factor 2 3.39195
NOTCH1 notch 1 3.38818
CYCS cytochrome c, somatic 3.35931
MYLK myosin light chain kinase 3.20978
CARMIL1 capping protein regulator and myosin 1 linker 1 3.19481
GARRE1 granule associated Rac and RHOG effector 1 3.14897
LYN LYN proto-oncogene, Src family tyrosine kinase 3.04144
CHMP6 charged multivesicular body protein 6 3.00599
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.91028
CIAO3 cytosolic iron-sulfur assembly component 3 2.90415
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.89078
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.75965
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.74726
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.74279
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.72372
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.69892
SFTPB surfactant protein B 2.6434
PLSCR1 phospholipid scramblase 1 2.56641
COPS7A COP9 signalosome subunit 7A 2.34406
ATP11B ATPase, class VI, type 11B 2.33627
STXBP2 syntaxin binding protein 2 2.1597
SATB1 SATB homeobox 1 2.11988
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 2.02634

decreased expression

Symbol Name Standardized Value
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.15182
UGDH UDP-glucose 6-dehydrogenase -3.54891
MRPS2 mitochondrial ribosomal protein S2 -3.35794
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.33667
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.29313
FBXL12 F-box and leucine-rich repeat protein 12 -3.27505
LDHD lactate dehydrogenase D -3.1176
EGF epidermal growth factor -3.02951
CDC20 cell division cycle 20 -2.64805
SLC35F2 solute carrier family 35, member F2 -2.61794
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.12043
OXA1L oxidase (cytochrome c) assembly 1-like -2.04836
RFC2 replication factor C (activator 1) 2, 40kDa -2.02735
INPP1 inositol polyphosphate-1-phosphatase -2.00637