CRCGN014_HEPG2_24H:C21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-nitronaphthalene 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN014_HEPG2_24H:C21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NOTCH1 notch 1 7.18507
PPARG peroxisome proliferator-activated receptor gamma 4.86349
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.78796
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.34342
CHN1 chimerin 1 3.29079
E2F2 E2F transcription factor 2 3.23969
GARRE1 granule associated Rac and RHOG effector 1 2.89271
CBR3 carbonyl reductase 3 2.74815
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.55647
PIH1D1 PIH1 domain containing 1 2.42981
JADE2 jade family PHD finger 2 2.29639
UBQLN2 ubiquilin 2 2.15499
MAP7 microtubule-associated protein 7 2.10947
CISD1 CDGSH iron sulfur domain 1 2.07481

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -4.22666
CD320 CD320 molecule -4.14549
FBXL12 F-box and leucine-rich repeat protein 12 -2.90605
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.87307
TLR4 toll-like receptor 4 -2.81216
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.80581
TM9SF3 transmembrane 9 superfamily member 3 -2.62034
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.58905
MRPS2 mitochondrial ribosomal protein S2 -2.50831
TM9SF2 transmembrane 9 superfamily member 2 -2.30898
REEP5 receptor accessory protein 5 -2.10125