CRCGN014_HEPG2_24H:C23 Gene Set
Genes
45 genes differentially expressed following the CRCGN014_HEPG2_24H:C23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.74309
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.08338
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.59576
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.00195
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.92141
|
|
UBQLN2
|
ubiquilin 2
|
3.08733
|
|
CYCS
|
cytochrome c, somatic
|
3.076
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.02237
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.81268
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.68452
|
|
HOXA10
|
homeobox A10
|
2.63099
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.55248
|
|
CHN1
|
chimerin 1
|
2.42338
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.19899
|
|
SATB1
|
SATB homeobox 1
|
2.17175
|
|
SFTPB
|
surfactant protein B
|
2.03616
|
|
KIF20A
|
kinesin family member 20A
|
2.00682
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-8.16356
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.46388
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.12308
|
|
ZNF586
|
zinc finger protein 586
|
-4.87475
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.74397
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.69185
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.04608
|
|
TWF2
|
twinfilin actin binding protein 2
|
-3.91765
|
|
TLR4
|
toll-like receptor 4
|
-3.73274
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.57272
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.51634
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-3.21514
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.19669
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.16555
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.08364
|
|
LDHD
|
lactate dehydrogenase D
|
-3.0666
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.02748
|
|
EGF
|
epidermal growth factor
|
-2.96085
|
|
WASHC4
|
WASH complex subunit 4
|
-2.77097
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.74527
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.70122
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.33598
|
|
DDX3Y
|
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
|
-2.32772
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.23899
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.18149
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.15477
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.07521
|
|
INSL4
|
insulin-like 4 (placenta)
|
-2.04813
|
