| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sorbic-acid 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN014_HEPG2_24H:C24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NOTCH1 | notch 1 | 6.79526 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.52723 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 6.30423 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.86648 |
| E2F2 | E2F transcription factor 2 | 4.55862 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 4.21122 |
| STIMATE | STIM activating enhancer | 3.56461 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.46748 |
| ADAM10 | ADAM metallopeptidase domain 10 | 3.20747 |
| SIRT3 | sirtuin 3 | 3.07978 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.92964 |
| ABHD6 | abhydrolase domain containing 6 | 2.90911 |
| MELK | maternal embryonic leucine zipper kinase | 2.71099 |
| PKN1 | protein kinase N1 | 2.62053 |
| CCNF | cyclin F | 2.56432 |
| AMH | anti-Mullerian hormone | 2.38579 |
| ADNP | activity-dependent neuroprotector homeobox | 2.34865 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 | 2.33859 |
| CHN1 | chimerin 1 | 2.33348 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.31498 |
| METRN | meteorin, glial cell differentiation regulator | 2.29691 |
| EPHA3 | EPH receptor A3 | 2.22556 |
| DNTT | DNA nucleotidylexotransferase | 2.2053 |
| TMEM59L | transmembrane protein 59-like | 2.18844 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 2.16046 |
| NIT2 | nitrilase family, member 2 | 2.1272 |
| FOXO3 | forkhead box O3 | 2.10774 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 2.1035 |
| LRRC15 | leucine rich repeat containing 15 | 2.08288 |
| ADAM11 | ADAM metallopeptidase domain 11 | 2.07226 |
| POMC | proopiomelanocortin | 2.04953 |
| PSPN | persephin | 2.04215 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.03579 |
| OSBP2 | oxysterol binding protein 2 | 2.02859 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GOLT1B | golgi transport 1B | -6.75468 |
| CDC20 | cell division cycle 20 | -5.0 |
| LDHD | lactate dehydrogenase D | -4.93145 |
| RGS2 | regulator of G-protein signaling 2 | -4.88981 |
| CCDC86 | coiled-coil domain containing 86 | -4.6954 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.65931 |
| TLR4 | toll-like receptor 4 | -4.10452 |
| PEG10 | paternally expressed 10 | -4.04052 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.70605 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.35819 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -3.30943 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.20052 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -2.91645 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.83993 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.70676 |
| ACLY | ATP citrate lyase | -2.68926 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.59196 |
| NES | nestin | -2.41414 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.35861 |
| DUSP6 | dual specificity phosphatase 6 | -2.31447 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.29607 |
| STX12 | syntaxin 12 | -2.16932 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -2.16157 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) | -2.15642 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -2.13045 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.12963 |
| HAT1 | histone acetyltransferase 1 | -2.09401 |
| SAP30BP | SAP30 binding protein | -2.02088 |
| PLSCR4 | phospholipid scramblase 4 | -2.01922 |
