| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | paracetamol 41.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN014_HEPG2_24H:D06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 8.89962 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 6.95133 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.91595 |
| CBR3 | carbonyl reductase 3 | 5.67604 |
| ADRB2 | adrenoceptor beta 2, surface | 5.19427 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.97647 |
| UBQLN2 | ubiquilin 2 | 4.84932 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.76755 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.3832 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.25808 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.20684 |
| MAP7 | microtubule-associated protein 7 | 4.09222 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.83268 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.79107 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.71647 |
| SQOR | sulfide quinone oxidoreductase | 3.67961 |
| SFTPB | surfactant protein B | 3.64342 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.18189 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 3.15836 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.00156 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.92046 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.79209 |
| BAX | BCL2-associated X protein | 2.75608 |
| BIRC2 | baculoviral IAP repeat containing 2 | 2.74289 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.7127 |
| CHN1 | chimerin 1 | 2.66414 |
| MCM3 | minichromosome maintenance complex component 3 | 2.60018 |
| PFKL | phosphofructokinase, liver | 2.54541 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.11904 |
| SKIC8 | SKI8 subunit of superkiller complex | 2.00015 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -5.79311 |
| MRPS2 | mitochondrial ribosomal protein S2 | -5.4071 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.31895 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.01622 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.44766 |
| VAT1 | vesicle amine transport 1 | -4.41835 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.33802 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.10256 |
| CHMP4B | charged multivesicular body protein 4B | -3.5068 |
| TLCD3A | TLC domain containing 3A | -3.26278 |
| RGS2 | regulator of G-protein signaling 2 | -3.10606 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -3.06633 |
| TES | testin LIM domain protein | -3.05592 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.04668 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.89866 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.83969 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -2.83617 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.62756 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.57079 |
| TLR4 | toll-like receptor 4 | -2.34131 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.25948 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -2.1917 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.13872 |
| YME1L1 | YME1-like 1 ATPase | -2.08757 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.01691 |
| SEC24C | SEC24 family member C | -2.00359 |
