| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4,4'-methylene-bis(2-methyl?aniline) 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
58 genes differentially expressed following the CRCGN014_HEPG2_24H:D09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 5.28838 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.11949 |
| STIMATE | STIM activating enhancer | 5.08736 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.84953 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 4.33863 |
| MOK | MOK protein kinase | 4.33347 |
| NOSIP | nitric oxide synthase interacting protein | 4.15322 |
| MAP7 | microtubule-associated protein 7 | 3.82672 |
| CDC45 | cell division cycle 45 | 3.2994 |
| SMIM40 | small integral membrane protein 40 | 3.28336 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.09256 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.92692 |
| PRKCH | protein kinase C, eta | 2.86136 |
| MCM3 | minichromosome maintenance complex component 3 | 2.81203 |
| SIRT3 | sirtuin 3 | 2.7637 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.66861 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.61969 |
| CEP57 | centrosomal protein 57kDa | 2.49543 |
| EPHA3 | EPH receptor A3 | 2.4578 |
| COPS7A | COP9 signalosome subunit 7A | 2.42441 |
| DIPK1A | divergent protein kinase domain 1A | 2.30534 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 | 2.21357 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.18196 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) | 2.16511 |
| FADD | Fas (TNFRSF6)-associated via death domain | 2.16319 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 2.1381 |
| RUNDC3B | RUN domain containing 3B | 2.08402 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 | 2.08184 |
| CHMP6 | charged multivesicular body protein 6 | 2.06152 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 2.01087 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.00609 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -9.57641 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.93255 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.29617 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.99509 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.86958 |
| ADI1 | acireductone dioxygenase 1 | -4.68935 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -4.67346 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -4.11297 |
| TLCD3A | TLC domain containing 3A | -3.84668 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.67553 |
| CCNB2 | cyclin B2 | -3.59554 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.31101 |
| SPAG4 | sperm associated antigen 4 | -3.12764 |
| HMG20B | high mobility group 20B | -2.91008 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.74216 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.72172 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.63207 |
| EGF | epidermal growth factor | -2.52626 |
| HTRA1 | HtrA serine peptidase 1 | -2.44627 |
| MTFR1 | mitochondrial fission regulator 1 | -2.42207 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.34711 |
| NIF3L1 | NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) | -2.2746 |
| NXT1 | nuclear transport factor 2-like export factor 1 | -2.15945 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.09321 |
| RBM15B | RNA binding motif protein 15B | -2.04867 |
| PPA2 | pyrophosphatase (inorganic) 2 | -2.04204 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -2.02641 |
