CRCGN014_HEPG2_24H:D14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN014_HEPG2_24H:D14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 5.38041
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.05763
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.96034
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.59896
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.40464
MOK MOK protein kinase 3.1855
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.12097
TXNL4B thioredoxin-like 4B 2.84738
LOC122526780 uncharacterized LOC122526780 2.60929
PIH1D1 PIH1 domain containing 1 2.49249
PRKCH protein kinase C, eta 2.36804
GPATCH8 G patch domain containing 8 2.20722
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.14429

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.7384
ZNF586 zinc finger protein 586 -5.39014
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.68875
CD320 CD320 molecule -4.36844
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.70329
ZDHHC6 zinc finger, DHHC-type containing 6 -3.3032
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -3.12221
EIF5 eukaryotic translation initiation factor 5 -2.63717
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.60248
TM9SF2 transmembrane 9 superfamily member 2 -2.41298
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.28266