CRCGN014_HEPG2_24H:D16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description trichlorofluoromethane 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN014_HEPG2_24H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHN1 chimerin 1 4.90789
BACE2 beta-site APP-cleaving enzyme 2 4.34772
MSRA methionine sulfoxide reductase A 3.76703
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.45758
STIMATE STIM activating enhancer 2.60625
TIAM1 T-cell lymphoma invasion and metastasis 1 2.48747
PRR15L proline rich 15-like 2.48257
LOC122526780 uncharacterized LOC122526780 2.46723
MAP7 microtubule-associated protein 7 2.4576
ABHD6 abhydrolase domain containing 6 2.38664
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.37714
CYCS cytochrome c, somatic 2.25931
HLA-DRA major histocompatibility complex, class II, DR alpha 2.24044
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.1739
PMM2 phosphomannomutase 2 2.12635
ZFP36 ZFP36 ring finger protein 2.10037

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -10.0
ZNF586 zinc finger protein 586 -5.14541
DNM1L dynamin 1-like -3.92462
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -3.58986
C2CD5 C2 calcium-dependent domain containing 5 -3.49194
TLR4 toll-like receptor 4 -3.00467
TLCD3A TLC domain containing 3A -2.81681
CCNB2 cyclin B2 -2.1701
OXA1L oxidase (cytochrome c) assembly 1-like -2.01019