CRCGN014_HEPG2_24H:D18 Gene Set
Genes
31 genes differentially expressed following the CRCGN014_HEPG2_24H:D18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.18107
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
5.12088
|
|
NOTCH1
|
notch 1
|
4.73103
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.41545
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.77052
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.96151
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.866
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.58383
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.4897
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.20344
|
|
PAXIP1
|
PAX interacting (with transcription-activation domain) protein 1
|
2.15683
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.09702
|
|
PSIP1
|
PC4 and SFRS1 interacting protein 1
|
2.03377
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PLK1
|
polo-like kinase 1
|
-7.73825
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.24011
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.10457
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-4.55422
|
|
LDHD
|
lactate dehydrogenase D
|
-4.41077
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.02149
|
|
CDC20
|
cell division cycle 20
|
-2.45278
|
|
GNAS
|
GNAS complex locus
|
-2.36041
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.35393
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.26169
|
|
CTNNAL1
|
catenin (cadherin-associated protein), alpha-like 1
|
-2.24674
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.21899
|
|
SLC10A2
|
solute carrier family 10 (sodium/bile acid cotransporter), member 2
|
-2.18034
|
|
TBL1XR1
|
transducin (beta)-like 1 X-linked receptor 1
|
-2.13173
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.12135
|
|
P2RX5
|
purinergic receptor P2X, ligand gated ion channel, 5
|
-2.1162
|
|
ADCYAP1
|
adenylate cyclase activating polypeptide 1 (pituitary)
|
-2.02249
|
|
FLT3
|
fms-related tyrosine kinase 3
|
-2.01562
|
