CRCGN014_HEPG2_24H:D23 Gene Set
Genes
33 genes differentially expressed following the CRCGN014_HEPG2_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.63552
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.24125
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
4.11791
|
|
STK10
|
serine/threonine kinase 10
|
4.01368
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.48602
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.27478
|
|
UBQLN2
|
ubiquilin 2
|
3.24148
|
|
EVL
|
Enah/Vasp-like
|
3.20624
|
|
MOK
|
MOK protein kinase
|
3.04698
|
|
CYCS
|
cytochrome c, somatic
|
2.73311
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.69088
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.68788
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.55528
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.30767
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.28862
|
|
SIRT3
|
sirtuin 3
|
2.12161
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-5.29036
|
|
RPS5
|
ribosomal protein S5
|
-3.90048
|
|
CCNB2
|
cyclin B2
|
-3.81057
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.79457
|
|
LDHD
|
lactate dehydrogenase D
|
-3.66729
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.58237
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.57865
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.53191
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.98754
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.83429
|
|
CCNB1
|
cyclin B1
|
-2.49821
|
|
CAB39
|
calcium binding protein 39
|
-2.42495
|
|
GNAS
|
GNAS complex locus
|
-2.42285
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.30186
|
|
RPL18
|
ribosomal protein L18
|
-2.20695
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.20337
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.1433
|
