| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | propyl gallate 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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64 genes differentially expressed following the CRCGN014_HEPG2_24H:D24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 5.66829 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 4.655 |
| TXNRD1 | thioredoxin reductase 1 | 4.19223 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 4.18453 |
| CDC45 | cell division cycle 45 | 3.90491 |
| DIPK1A | divergent protein kinase domain 1A | 3.70789 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.67862 |
| ABHD4 | abhydrolase domain containing 4 | 3.60867 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.52474 |
| NOTCH1 | notch 1 | 3.46118 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.21755 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.17311 |
| EVL | Enah/Vasp-like | 3.12892 |
| HMOX1 | heme oxygenase 1 | 3.11725 |
| KEAP1 | kelch-like ECH-associated protein 1 | 3.11166 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.09987 |
| EPHB2 | EPH receptor B2 | 3.0354 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 3.0105 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 2.96519 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.96373 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.88944 |
| SFTPB | surfactant protein B | 2.86667 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 2.75644 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 2.6794 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.57317 |
| CHMP6 | charged multivesicular body protein 6 | 2.55324 |
| TENT4A | terminal nucleotidyltransferase 4A | 2.36749 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 2.33114 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.29696 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.2 |
| TBC1D31 | TBC1 domain family, member 31 | 2.17953 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.11006 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.10616 |
| KDM3A | lysine (K)-specific demethylase 3A | 2.08366 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.72586 |
| CDC20 | cell division cycle 20 | -5.49841 |
| SLC35F2 | solute carrier family 35, member F2 | -5.10312 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -3.99181 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.97383 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.78983 |
| PLK1 | polo-like kinase 1 | -3.62487 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.61196 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -3.5459 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -3.05401 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.97553 |
| TLR4 | toll-like receptor 4 | -2.96959 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.81329 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.66689 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.64463 |
| ILK | integrin-linked kinase | -2.59017 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.51799 |
| NUP62 | nucleoporin 62kDa | -2.47743 |
| CD320 | CD320 molecule | -2.46747 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.4168 |
| MYL9 | myosin, light chain 9, regulatory | -2.37345 |
| GNAS | GNAS complex locus | -2.31278 |
| CDC25B | cell division cycle 25B | -2.30758 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.27601 |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) | -2.12729 |
| CCNB2 | cyclin B2 | -2.12282 |
| ZNF862 | zinc finger protein 862 | -2.12218 |
| PUF60 | poly-U binding splicing factor 60KDa | -2.0443 |
| CYTL1 | cytokine-like 1 | -2.03901 |
| HAT1 | histone acetyltransferase 1 | -2.01544 |