| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methapyrilene 20.82 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN014_HEPG2_24H:E02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL39L | ribosomal protein L39-like | 5.77591 |
| MAP7 | microtubule-associated protein 7 | 5.72862 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.65728 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 5.44599 |
| GSTZ1 | glutathione S-transferase zeta 1 | 5.4351 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.21917 |
| NOTCH1 | notch 1 | 4.82321 |
| ADRB2 | adrenoceptor beta 2, surface | 4.74467 |
| UBQLN2 | ubiquilin 2 | 4.68258 |
| ABHD6 | abhydrolase domain containing 6 | 4.58584 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.45758 |
| STAP2 | signal transducing adaptor family member 2 | 4.32057 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.16153 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.61701 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.29054 |
| EPN2 | epsin 2 | 3.01475 |
| LSR | lipolysis stimulated lipoprotein receptor | 2.93537 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.9036 |
| GATA2 | GATA binding protein 2 | 2.85808 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 2.79453 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.57791 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.47044 |
| LCN2 | lipocalin 2 | 2.36317 |
| FOXJ1 | forkhead box J1 | 2.16865 |
| KIF20A | kinesin family member 20A | 2.11307 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 | 2.07211 |
| HPGDS | hematopoietic prostaglandin D synthase | 2.06233 |
| NOSIP | nitric oxide synthase interacting protein | 2.04475 |
| TBXA2R | thromboxane A2 receptor | 2.02053 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 2.00907 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -8.97713 |
| TLR4 | toll-like receptor 4 | -5.29559 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -5.03548 |
| MRPS16 | mitochondrial ribosomal protein S16 | -4.59368 |
| FASTKD5 | FAST kinase domains 5 | -4.17823 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.16802 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.09347 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -4.0903 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.20939 |
| SNX11 | sorting nexin 11 | -2.93715 |
| EGF | epidermal growth factor | -2.90052 |
| CCNB2 | cyclin B2 | -2.64954 |
| SLC35F2 | solute carrier family 35, member F2 | -2.64343 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.6009 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.55447 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.43408 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.32959 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | -2.27231 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.12132 |
| WASHC4 | WASH complex subunit 4 | -2.07328 |
| MBD1 | methyl-CpG binding domain protein 1 | -2.06776 |
| RAI14 | retinoic acid induced 14 | -2.06052 |
| ZNF12 | zinc finger protein 12 | -2.02277 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.01397 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.0108 |
