CRCGN014_HEPG2_24H:E03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-butyl chloride 40.8 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

43 genes differentially expressed following the CRCGN014_HEPG2_24H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.86918
NOTCH1 notch 1 4.75393
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.67885
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.66568
SNAP25 synaptosomal-associated protein, 25kDa 4.467
PRR15L proline rich 15-like 4.32401
CHN1 chimerin 1 4.29721
INTS3 integrator complex subunit 3 3.86905
ABHD6 abhydrolase domain containing 6 3.45942
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.43253
EPHA3 EPH receptor A3 3.34557
UBQLN2 ubiquilin 2 3.07798
RXYLT1 ribitol xylosyltransferase 1 2.99756
CARMIL1 capping protein regulator and myosin 1 linker 1 2.9535
CBR3 carbonyl reductase 3 2.9089
ATP11B ATPase, class VI, type 11B 2.75741
PNKP polynucleotide kinase 3'-phosphatase 2.7446
RAB21 RAB21, member RAS oncogene family 2.64934
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.54133
LOC122526780 uncharacterized LOC122526780 2.50542
ABHD3 abhydrolase domain containing 3 2.18026
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 2.16289
FPGS folylpolyglutamate synthase 2.16276
RUBCNL rubicon like autophagy enhancer 2.11995
CGRRF1 cell growth regulator with ring finger domain 1 2.09707
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.04326
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.02088

decreased expression

Symbol Name Standardized Value
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -8.26233
FBXL12 F-box and leucine-rich repeat protein 12 -6.00363
GOLT1B golgi transport 1B -5.09202
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.8003
FASTKD5 FAST kinase domains 5 -4.68654
GDF15 growth differentiation factor 15 -3.70309
COG7 component of oligomeric golgi complex 7 -3.56625
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -3.41154
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.34031
NRIP1 nuclear receptor interacting protein 1 -2.73167
TRIB3 tribbles pseudokinase 3 -2.72184
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.70686
OXA1L oxidase (cytochrome c) assembly 1-like -2.61362
TLCD3A TLC domain containing 3A -2.52036
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.32805
RNF167 ring finger protein 167 -2.03433