CRCGN014_HEPG2_24H:E04 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_24H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
6.21604
|
|
ATP11B
|
ATPase, class VI, type 11B
|
5.5211
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.88713
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.96938
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.81437
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.75836
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.71349
|
|
CHN1
|
chimerin 1
|
3.67608
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.49622
|
|
STK10
|
serine/threonine kinase 10
|
3.45351
|
|
MYLK
|
myosin light chain kinase
|
3.35115
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.34297
|
|
HOXA10
|
homeobox A10
|
3.05914
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.94698
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.74029
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.60559
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.48037
|
|
UBQLN2
|
ubiquilin 2
|
2.38326
|
|
KLHL21
|
kelch-like family member 21
|
2.328
|
|
PLS1
|
plastin 1
|
2.3262
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.14556
|
|
NUSAP1
|
nucleolar and spindle associated protein 1
|
2.14434
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.03065
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.00583
|
|
SMIM40
|
small integral membrane protein 40
|
2.00036
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.59195
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.53153
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.21012
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.15855
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.76336
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.65269
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.37901
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.37494
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.34643
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.32366
|
|
LDHD
|
lactate dehydrogenase D
|
-2.26484
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.25779
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.13692
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.02848
|
|
RNF167
|
ring finger protein 167
|
-2.01249
|
