| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tin (ii) chloride 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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52 genes differentially expressed following the CRCGN014_HEPG2_24H:E05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 7.34151 |
| SQOR | sulfide quinone oxidoreductase | 6.33552 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.95301 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.56012 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 3.68456 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.46558 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.45134 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.37818 |
| RPL39L | ribosomal protein L39-like | 3.24043 |
| STK10 | serine/threonine kinase 10 | 3.1758 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 3.11586 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.00147 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.98795 |
| MAMLD1 | mastermind-like domain containing 1 | 2.98674 |
| INTS3 | integrator complex subunit 3 | 2.90402 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.89355 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.89216 |
| SFTPB | surfactant protein B | 2.75527 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.75387 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.66208 |
| MYLK | myosin light chain kinase | 2.61953 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.47119 |
| STIMATE | STIM activating enhancer | 2.24204 |
| GATA3 | GATA binding protein 3 | 2.15039 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 2.10262 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.0587 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 2.02992 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAPK13 | mitogen-activated protein kinase 13 | -5.27704 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.97756 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.75324 |
| TLR4 | toll-like receptor 4 | -3.75316 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.61884 |
| ADI1 | acireductone dioxygenase 1 | -3.61828 |
| TP53BP2 | tumor protein p53 binding protein 2 | -3.4669 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.44629 |
| LAP3 | leucine aminopeptidase 3 | -3.32543 |
| CAB39 | calcium binding protein 39 | -3.31183 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.30152 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.269 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.97997 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.93608 |
| CD320 | CD320 molecule | -2.87042 |
| FHL2 | four and a half LIM domains 2 | -2.77134 |
| GTPBP8 | GTP-binding protein 8 (putative) | -2.68916 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.68004 |
| PUF60 | poly-U binding splicing factor 60KDa | -2.64316 |
| CDC20 | cell division cycle 20 | -2.58659 |
| CDC25B | cell division cycle 25B | -2.43838 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -2.40211 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.38409 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -2.21148 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.04342 |