CRCGN014_HEPG2_24H:E08 Gene Set
Genes
45 genes differentially expressed following the CRCGN014_HEPG2_24H:E08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
7.0165
|
|
CHMP6
|
charged multivesicular body protein 6
|
5.88495
|
|
UBQLN2
|
ubiquilin 2
|
5.3155
|
|
NOTCH1
|
notch 1
|
5.3151
|
|
CYCS
|
cytochrome c, somatic
|
4.89565
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.84025
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
4.73815
|
|
GATA3
|
GATA binding protein 3
|
3.4765
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.36505
|
|
ZNF589
|
zinc finger protein 589
|
3.35418
|
|
PRR15L
|
proline rich 15-like
|
3.08315
|
|
CHN1
|
chimerin 1
|
3.0725
|
|
PMM2
|
phosphomannomutase 2
|
3.03
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.828
|
|
SNX7
|
sorting nexin 7
|
2.60515
|
|
KIF20A
|
kinesin family member 20A
|
2.3759
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.3405
|
|
MTX2
|
metaxin 2
|
2.16145
|
|
RFTN1
|
raftlin, lipid raft linker 1
|
2.1605
|
|
COQ9
|
coenzyme Q9
|
2.1019
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-5.1988
|
|
ZNF586
|
zinc finger protein 586
|
-5.1215
|
|
CD320
|
CD320 molecule
|
-5.0468
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-5.0
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.9356
|
|
CDC20
|
cell division cycle 20
|
-4.8605
|
|
LDHD
|
lactate dehydrogenase D
|
-4.7944
|
|
ZW10
|
zw10 kinetochore protein
|
-3.5392
|
|
CCNB2
|
cyclin B2
|
-3.03285
|
|
EGF
|
epidermal growth factor
|
-2.64605
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.57792
|
|
TBP
|
TATA box binding protein
|
-2.57315
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.45703
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.457
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.42495
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.41275
|
|
ARID4A
|
AT rich interactive domain 4A (RBP1-like)
|
-2.2255
|
|
UBAP1
|
ubiquitin associated protein 1
|
-2.16563
|
|
PCBP4
|
poly(rC) binding protein 4
|
-2.0757
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.0683
|
|
MXRA8
|
matrix-remodelling associated 8
|
-2.0139
|
|
EPCAM
|
epithelial cell adhesion molecule
|
-2.0127
|
|
CD4
|
CD4 molecule
|
-2.01095
|
|
PXDNL
|
peroxidasin-like
|
-2.00975
|
|
STXBP1
|
syntaxin binding protein 1
|
-2.00755
|