CRCGN014_HEPG2_24H:E11 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_24H:E11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
5.36084
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.79726
|
|
E2F2
|
E2F transcription factor 2
|
3.69791
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.66374
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
3.42982
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.40852
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.34038
|
|
LCN2
|
lipocalin 2
|
3.19249
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.13312
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.53578
|
|
MICALL1
|
MICAL-like 1
|
2.53504
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.40922
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.32
|
|
CRTAP
|
cartilage associated protein
|
2.27638
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.25179
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.22899
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.09451
|
|
PNPLA3
|
patatin-like phospholipase domain containing 3
|
2.08758
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
2.07754
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CD320
|
CD320 molecule
|
-6.80784
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.23935
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-4.09368
|
|
DSG2
|
desmoglein 2
|
-3.93276
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.43416
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.38621
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.97766
|
|
GNAS
|
GNAS complex locus
|
-2.93532
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.83686
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.67681
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.29313
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.16081
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.09102
|
|
RHEB
|
Ras homolog enriched in brain
|
-2.07793
|
|
CST2
|
cystatin SA
|
-2.03714
|
|
PPOX
|
protoporphyrinogen oxidase
|
-2.03638
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.00214
|
