CRCGN014_HEPG2_24H:E12 Gene Set
Genes
45 genes differentially expressed following the CRCGN014_HEPG2_24H:E12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
8.34302
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
5.49831
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.15387
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.10037
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.93105
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.57253
|
|
STIMATE
|
STIM activating enhancer
|
4.2857
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.87305
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.63361
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
3.63333
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.20761
|
|
LCN2
|
lipocalin 2
|
3.14584
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.12097
|
|
CBR3
|
carbonyl reductase 3
|
3.11797
|
|
PMM2
|
phosphomannomutase 2
|
3.02054
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.98656
|
|
PRKCQ
|
protein kinase C, theta
|
2.96936
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.94133
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.91887
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
2.91155
|
|
PRR15L
|
proline rich 15-like
|
2.90936
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.83544
|
|
CHN1
|
chimerin 1
|
2.36772
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.34232
|
|
SATB1
|
SATB homeobox 1
|
2.31526
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.09243
|
|
PFKL
|
phosphofructokinase, liver
|
2.05152
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-5.17998
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.97098
|
|
DSG2
|
desmoglein 2
|
-3.95236
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.75232
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.70999
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.56034
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.53844
|
|
CDC20
|
cell division cycle 20
|
-3.45104
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.29326
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.16
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.90824
|
|
CDC25B
|
cell division cycle 25B
|
-2.64391
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.5
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.47884
|
|
REEP5
|
receptor accessory protein 5
|
-2.35349
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.33202
|
|
WASHC4
|
WASH complex subunit 4
|
-2.24879
|
|
TLR4
|
toll-like receptor 4
|
-2.16627
|
