CRCGN014_HEPG2_24H:E14 Gene Set
Genes
34 genes differentially expressed following the CRCGN014_HEPG2_24H:E14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.11359
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.1636
|
|
UBQLN2
|
ubiquilin 2
|
3.92115
|
|
NOTCH1
|
notch 1
|
3.63946
|
|
SFTPB
|
surfactant protein B
|
3.55968
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.49258
|
|
PMM2
|
phosphomannomutase 2
|
3.30804
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.27415
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
3.1274
|
|
HDGFL3
|
HDGF like 3
|
3.11747
|
|
CYCS
|
cytochrome c, somatic
|
3.02065
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.84963
|
|
MEF2C
|
myocyte enhancer factor 2C
|
2.84383
|
|
KIF20A
|
kinesin family member 20A
|
2.481
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.46093
|
|
EPN2
|
epsin 2
|
2.44609
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.35904
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.28501
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.09471
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.0947
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.06798
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.03491
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
ZNF586
|
zinc finger protein 586
|
-4.05209
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.32126
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.01837
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.98651
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.68916
|
|
CDC20
|
cell division cycle 20
|
-2.68546
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.62152
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.61906
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.34863
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.22113
|
|
SQSTM1
|
sequestosome 1
|
-2.16877
|
