| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tert-butylhydroquinone 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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62 genes differentially expressed following the CRCGN014_HEPG2_24H:E17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.95684 |
| TXNRD1 | thioredoxin reductase 1 | 5.78465 |
| ABHD4 | abhydrolase domain containing 4 | 4.55865 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 4.12992 |
| STK10 | serine/threonine kinase 10 | 3.51341 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.49814 |
| UBQLN2 | ubiquilin 2 | 3.4959 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 3.3835 |
| KEAP1 | kelch-like ECH-associated protein 1 | 3.17522 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.86744 |
| MAP7 | microtubule-associated protein 7 | 2.72129 |
| CTSL | cathepsin L | 2.71591 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.69017 |
| CYCS | cytochrome c, somatic | 2.5555 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.53718 |
| KIF5C | kinesin family member 5C | 2.53711 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.36978 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 2.3665 |
| NOSIP | nitric oxide synthase interacting protein | 2.36023 |
| AXIN1 | axin 1 | 2.34939 |
| MCM3 | minichromosome maintenance complex component 3 | 2.33412 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.28538 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.24949 |
| GRB10 | growth factor receptor-bound protein 10 | 2.20135 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 2.15982 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 2.14808 |
| TEX10 | testis expressed 10 | 2.14104 |
| ADSS2 | adenylosuccinate synthase 2 | 2.08025 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.07601 |
| CBR1 | carbonyl reductase 1 | 2.05725 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.03993 |
| FOSL1 | FOS-like antigen 1 | 2.03051 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCAND1 | SCAN domain containing 1 | -7.02697 |
| GNAS | GNAS complex locus | -4.73294 |
| CCNB2 | cyclin B2 | -3.90416 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.61383 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.54478 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -3.49645 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.18937 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.15524 |
| TRIB3 | tribbles pseudokinase 3 | -3.10526 |
| CDC20 | cell division cycle 20 | -3.05887 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -2.75214 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.65559 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.64076 |
| LDHD | lactate dehydrogenase D | -2.54874 |
| PEG10 | paternally expressed 10 | -2.43546 |
| ASL | argininosuccinate lyase | -2.38623 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.28799 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.26886 |
| FAIM | Fas apoptotic inhibitory molecule | -2.245 |
| EGF | epidermal growth factor | -2.17321 |
| GDF15 | growth differentiation factor 15 | -2.17055 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.16566 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | -2.13739 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.12782 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.11988 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -2.0718 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.04775 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -2.0405 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -2.02835 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.00033 |
