CRCGN014_HEPG2_24H:E18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description resorcinol 39.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

104 genes differentially expressed following the CRCGN014_HEPG2_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MOK MOK protein kinase 7.73862
TIAM1 T-cell lymphoma invasion and metastasis 1 5.86859
PNKP polynucleotide kinase 3'-phosphatase 5.78488
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.97419
ADGRE5 adhesion G protein-coupled receptor E5 4.73155
HLA-DMA major histocompatibility complex, class II, DM alpha 4.70675
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.37317
RPP38 ribonuclease P/MRP 38kDa subunit 4.30758
SNAP25 synaptosomal-associated protein, 25kDa 4.28306
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.20765
MSRA methionine sulfoxide reductase A 4.17808
CCDC85B coiled-coil domain containing 85B 4.10754
PLS1 plastin 1 4.01691
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 3.97402
BACE2 beta-site APP-cleaving enzyme 2 3.89366
CCNF cyclin F 3.75521
CARMIL1 capping protein regulator and myosin 1 linker 1 3.68969
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.52212
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.29997
GPER1 G protein-coupled estrogen receptor 1 3.2538
CHN1 chimerin 1 3.05956
PPARG peroxisome proliferator-activated receptor gamma 3.03757
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.99033
MXRA8 matrix-remodelling associated 8 2.89723
LYN LYN proto-oncogene, Src family tyrosine kinase 2.87312
ZNF516 zinc finger protein 516 2.81762
PEX11A peroxisomal biogenesis factor 11 alpha 2.72627
KIF20A kinesin family member 20A 2.69004
HLA-DRA major histocompatibility complex, class II, DR alpha 2.6344
DYNLT3 dynein, light chain, Tctex-type 3 2.61337
VGLL4 vestigial-like family member 4 2.49733
LRRC40 leucine rich repeat containing 40 2.45562
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 2.45264
STIMATE STIM activating enhancer 2.45238
GSTZ1 glutathione S-transferase zeta 1 2.42985
CEP57 centrosomal protein 57kDa 2.41012
SH3GL2 SH3-domain GRB2-like 2 2.35879
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 2.32411
PPP1R17 protein phosphatase 1, regulatory subunit 17 2.31895
LPXN leupaxin 2.24535
PLSCR3 phospholipid scramblase 3 2.24268
RBMS3 RNA binding motif, single stranded interacting protein 3 2.21926
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.21858
ACO1 aconitase 1, soluble 2.17776
JRKL JRK-like 2.17045
TCEAL4 transcription elongation factor A (SII)-like 4 2.16379
VEGFC vascular endothelial growth factor C 2.14325
ISLR immunoglobulin superfamily containing leucine-rich repeat 2.13764
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.12719
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.12434
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.12381
SH3D19 SH3 domain containing 19 2.09907
MINDY3 MINDY lysine 48 deubiquitinase 3 2.08443
ZNF589 zinc finger protein 589 2.0442
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.01035
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 2.00798

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -8.7599
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -5.8586
PCNA proliferating cell nuclear antigen -5.54955
NGRN neugrin, neurite outgrowth associated -5.4618
DSG2 desmoglein 2 -4.88379
TP53BP2 tumor protein p53 binding protein 2 -4.72436
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.58942
RFC2 replication factor C (activator 1) 2, 40kDa -4.56509
RPIA ribose 5-phosphate isomerase A -4.5564
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.46117
NUP93 nucleoporin 93kDa -4.44988
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.43322
KDM3A lysine (K)-specific demethylase 3A -4.24143
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -4.20259
LAP3 leucine aminopeptidase 3 -4.16902
THAP11 THAP domain containing 11 -4.1141
CHMP4B charged multivesicular body protein 4B -3.73158
FAIM Fas apoptotic inhibitory molecule -3.71204
ITFG1 integrin alpha FG-GAP repeat containing 1 -3.5973
RBM34 RNA binding motif protein 34 -3.39173
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.16973
YME1L1 YME1-like 1 ATPase -2.93923
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.75285
HMG20B high mobility group 20B -2.7367
CCNB1 cyclin B1 -2.60459
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -2.52817
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -2.5082
TCTN1 tectonic family member 1 -2.33399
CDK18 cyclin-dependent kinase 18 -2.3223
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -2.31034
PAQR6 progestin and adipoQ receptor family member VI -2.28092
ADI1 acireductone dioxygenase 1 -2.2491
ANKRD10 ankyrin repeat domain 10 -2.18153
GNAS GNAS complex locus -2.16148
CLIP2 CAP-GLY domain containing linker protein 2 -2.10585
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.08571
RSAD2 radical S-adenosyl methionine domain containing 2 -2.07036
CTSD cathepsin D -2.06596
FHOD1 formin homology 2 domain containing 1 -2.0522
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -2.0404
CHMP1A charged multivesicular body protein 1A -2.03876
CEP170B centrosomal protein 170B -2.03787
TUBB4A tubulin, beta 4A class IVa -2.02945
NVL nuclear VCP-like -2.02542
TBCB tubulin folding cofactor B -2.0191
KCTD13 potassium channel tetramerization domain containing 13 -2.01685
SRP9 signal recognition particle 9kDa -2.01501
CDC25B cell division cycle 25B -2.0105