CRCGN014_HEPG2_24H:E22 Gene Set
Genes
51 genes differentially expressed following the CRCGN014_HEPG2_24H:E22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.20315
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
5.60288
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
5.29053
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.88463
|
|
EVL
|
Enah/Vasp-like
|
4.73527
|
|
MAP7
|
microtubule-associated protein 7
|
4.32293
|
|
E2F2
|
E2F transcription factor 2
|
4.20223
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
3.63585
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.37309
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.31388
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.14466
|
|
ZNF589
|
zinc finger protein 589
|
2.88772
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.85654
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.80679
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.58259
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.49289
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.43513
|
|
STK10
|
serine/threonine kinase 10
|
2.31922
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.2603
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.20999
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.14894
|
|
CCNA1
|
cyclin A1
|
2.14609
|
|
KAT6A
|
K(lysine) acetyltransferase 6A
|
2.12427
|
|
TTYH1
|
tweety family member 1
|
2.04495
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.00273
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.7698
|
|
ZNF586
|
zinc finger protein 586
|
-6.004
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.89467
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-5.16539
|
|
GNAS
|
GNAS complex locus
|
-5.00125
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.90333
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.80687
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.80361
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-4.28891
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-4.12132
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.51735
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
-3.45906
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.10977
|
|
TLR4
|
toll-like receptor 4
|
-2.81161
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.78314
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.69269
|
|
GOLT1B
|
golgi transport 1B
|
-2.57062
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.55165
|
|
CDC20
|
cell division cycle 20
|
-2.35215
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.21889
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.19345
|
|
TINF2
|
TERF1 (TRF1)-interacting nuclear factor 2
|
-2.14955
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-2.03331
|
|
PPL
|
periplakin
|
-2.02404
|
|
EDN3
|
endothelin 3
|
-2.02341
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.00737
|
