CRCGN014_HEPG2_24H:E23 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_24H:E23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.18213
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
4.97925
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.90702
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.86496
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
4.84175
|
|
PIH1D1
|
PIH1 domain containing 1
|
4.27349
|
|
INTS3
|
integrator complex subunit 3
|
3.96495
|
|
AXIN1
|
axin 1
|
3.41833
|
|
CHN1
|
chimerin 1
|
3.41297
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.36873
|
|
FBXO7
|
F-box protein 7
|
3.26234
|
|
MYLK
|
myosin light chain kinase
|
3.07734
|
|
GPATCH8
|
G patch domain containing 8
|
2.9313
|
|
TBPL1
|
TBP-like 1
|
2.80318
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.61703
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.56366
|
|
PMM2
|
phosphomannomutase 2
|
2.47326
|
|
P2RY10
|
purinergic receptor P2Y, G-protein coupled, 10
|
2.21095
|
|
GATA3
|
GATA binding protein 3
|
2.19221
|
|
CCL11
|
chemokine (C-C motif) ligand 11
|
2.16504
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.11296
|
|
POMT1
|
protein-O-mannosyltransferase 1
|
2.01396
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-5.25421
|
|
LDHD
|
lactate dehydrogenase D
|
-4.99648
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.94584
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.82099
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.94873
|
|
NUP93
|
nucleoporin 93kDa
|
-3.87147
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.56528
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.33656
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.219
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.19277
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.04286
|
|
LYPLA1
|
lysophospholipase I
|
-2.87386
|
|
CDK20
|
cyclin-dependent kinase 20
|
-2.38234
|
|
PGM1
|
phosphoglucomutase 1
|
-2.31511
|
|
EGF
|
epidermal growth factor
|
-2.28627
|
|
AAMP
|
angio-associated, migratory cell protein
|
-2.22871
|
|
BBS7
|
Bardet-Biedl syndrome 7
|
-2.18767
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.07247
|
