CRCGN014_HEPG2_24H:E24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aspirin 39.8 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN014_HEPG2_24H:E24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.58542
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.26806
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.18719
SFTPB surfactant protein B 4.05342
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.01687
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.95313
UBQLN2 ubiquilin 2 3.92815
MOK MOK protein kinase 3.65798
JADE2 jade family PHD finger 2 3.26898
ANO1 anoctamin 1, calcium activated chloride channel 3.23451
C2CD2 C2 calcium-dependent domain containing 2 3.18451
CIAO3 cytosolic iron-sulfur assembly component 3 3.1676
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.89586
STIMATE STIM activating enhancer 2.78217
ATP11B ATPase, class VI, type 11B 2.69588
KLHL9 kelch-like family member 9 2.31097
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.30286
PRR15L proline rich 15-like 2.21202
CXCL2 chemokine (C-X-C motif) ligand 2 2.10169
PFKL phosphofructokinase, liver 2.07565
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.0232

decreased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 -3.91263
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.84798
FASTKD5 FAST kinase domains 5 -3.53143
CDC20 cell division cycle 20 -3.3497
FBXL12 F-box and leucine-rich repeat protein 12 -3.10033
TWF2 twinfilin actin binding protein 2 -2.69524
LDHD lactate dehydrogenase D -2.58487
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.3381
SLC35F2 solute carrier family 35, member F2 -2.02722
REEP5 receptor accessory protein 5 -2.01341