CRCGN014_HEPG2_24H:F04 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_24H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.17379
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.93489
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.61613
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
3.29077
|
|
UBQLN2
|
ubiquilin 2
|
3.20792
|
|
GPATCH8
|
G patch domain containing 8
|
3.19399
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.9946
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.76162
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.70733
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.54823
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.52001
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
2.51843
|
|
CCDC86
|
coiled-coil domain containing 86
|
2.47225
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
2.4477
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.36092
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.19698
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.18935
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GDF15
|
growth differentiation factor 15
|
-6.62497
|
|
ZNF586
|
zinc finger protein 586
|
-5.02153
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.38682
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.23184
|
|
CD320
|
CD320 molecule
|
-3.15975
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.00801
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-2.91276
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.76361
|
|
LDHD
|
lactate dehydrogenase D
|
-2.58187
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.34713
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.33069
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.27548
|
|
CTNNAL1
|
catenin (cadherin-associated protein), alpha-like 1
|
-2.1939
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.18969
|
|
ERBIN
|
erbb2 interacting protein
|
-2.13615
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
-2.09667
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.04447
|
|
RPS5
|
ribosomal protein S5
|
-2.04056
|
