CRCGN014_HEPG2_24H:F05 Gene Set
Genes
52 genes differentially expressed following the CRCGN014_HEPG2_24H:F05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
7.08088
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.81232
|
|
NOTCH1
|
notch 1
|
4.68037
|
|
MOK
|
MOK protein kinase
|
4.58863
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.35251
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
4.03498
|
|
HOXA10
|
homeobox A10
|
4.0062
|
|
EPN2
|
epsin 2
|
3.57276
|
|
CBR3
|
carbonyl reductase 3
|
3.52541
|
|
MYLK
|
myosin light chain kinase
|
3.26309
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.25916
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.15581
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.14413
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.05212
|
|
GATA3
|
GATA binding protein 3
|
2.90135
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.84296
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.73845
|
|
PRR15L
|
proline rich 15-like
|
2.72799
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.58562
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
2.48405
|
|
CHEK2
|
checkpoint kinase 2
|
2.31685
|
|
AXIN1
|
axin 1
|
2.2707
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.03382
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.03199
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNM1L
|
dynamin 1-like
|
-5.10722
|
|
GOLT1B
|
golgi transport 1B
|
-4.95999
|
|
TSPAN4
|
tetraspanin 4
|
-4.93586
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.64295
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.35419
|
|
GNAS
|
GNAS complex locus
|
-3.77842
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.66371
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-3.44236
|
|
TLR4
|
toll-like receptor 4
|
-3.3954
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.34545
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.9055
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.88609
|
|
LDHD
|
lactate dehydrogenase D
|
-2.69625
|
|
RNF167
|
ring finger protein 167
|
-2.65115
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.55618
|
|
SH3GL3
|
SH3-domain GRB2-like 3
|
-2.42018
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.41226
|
|
PEG10
|
paternally expressed 10
|
-2.3303
|
|
RTN1
|
reticulon 1
|
-2.32004
|
|
CDC20
|
cell division cycle 20
|
-2.27188
|
|
SNX11
|
sorting nexin 11
|
-2.26042
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.22879
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.17247
|
|
EBNA1BP2
|
EBNA1 binding protein 2
|
-2.12008
|
|
SLC10A3
|
solute carrier family 10, member 3
|
-2.11981
|
|
ZNF711
|
zinc finger protein 711
|
-2.1096
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.07722
|
|
TWSG1
|
twisted gastrulation BMP signaling modulator 1
|
-2.0274
|
