CRCGN014_HEPG2_24H:F06 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_24H:F06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.41376
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.99885
|
|
PRR15L
|
proline rich 15-like
|
3.76101
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.45226
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.01029
|
|
STK10
|
serine/threonine kinase 10
|
2.82784
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.74835
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.67348
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.66294
|
|
NOTCH1
|
notch 1
|
2.63961
|
|
EPHB2
|
EPH receptor B2
|
2.59452
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.541
|
|
UBQLN2
|
ubiquilin 2
|
2.30594
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
2.20059
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.19392
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.07981
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.31683
|
|
PLK1
|
polo-like kinase 1
|
-4.08907
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.94388
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.86308
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.70119
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.99319
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.83658
|
|
TLR4
|
toll-like receptor 4
|
-2.82166
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.80764
|
|
LDHD
|
lactate dehydrogenase D
|
-2.70454
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.64108
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.60947
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.60534
|
|
CDC25B
|
cell division cycle 25B
|
-2.48922
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.38876
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.35228
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
-2.2037
|
|
NVL
|
nuclear VCP-like
|
-2.03929
|
|
HMG20B
|
high mobility group 20B
|
-2.01792
|
