| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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120 genes differentially expressed following the CRCGN014_HEPG2_24H:F07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.86778 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 6.44087 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.85885 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 4.74145 |
| ADRB2 | adrenoceptor beta 2, surface | 4.57265 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.27015 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.15297 |
| E2F2 | E2F transcription factor 2 | 4.06693 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.03799 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 3.89867 |
| MEF2C | myocyte enhancer factor 2C | 3.86571 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.83251 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.78807 |
| ATP11B | ATPase, class VI, type 11B | 3.73954 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.73143 |
| EPHA3 | EPH receptor A3 | 3.7224 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.66068 |
| CCDC92 | coiled-coil domain containing 92 | 3.61678 |
| HDGFL3 | HDGF like 3 | 3.55196 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.47839 |
| GPATCH8 | G patch domain containing 8 | 3.14642 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.12758 |
| IDE | insulin-degrading enzyme | 3.00732 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.96858 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.9054 |
| GATA3 | GATA binding protein 3 | 2.87647 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.77897 |
| AMPD1 | adenosine monophosphate deaminase 1 | 2.68431 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.68012 |
| KDM5A | lysine (K)-specific demethylase 5A | 2.66643 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.61945 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.60667 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.6052 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.48178 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.4693 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.46373 |
| PRR15L | proline rich 15-like | 2.4443 |
| MICALL1 | MICAL-like 1 | 2.39181 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.38328 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.34234 |
| GRB10 | growth factor receptor-bound protein 10 | 2.31045 |
| RAB21 | RAB21, member RAS oncogene family | 2.28931 |
| MAP7 | microtubule-associated protein 7 | 2.27609 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 2.25168 |
| OMD | osteomodulin | 2.2469 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.22754 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 2.22051 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.17382 |
| JUN | jun proto-oncogene | 2.1446 |
| CASQ2 | calsequestrin 2 (cardiac muscle) | 2.13967 |
| ABHD4 | abhydrolase domain containing 4 | 2.12198 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.11681 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.07162 |
| CHN1 | chimerin 1 | 2.06609 |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 | 2.03653 |
| KAT6B | K(lysine) acetyltransferase 6B | 2.03326 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 2.03227 |
| DMAP1 | DNA methyltransferase 1 associated protein 1 | 2.02913 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 2.01586 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | 2.00731 |
| IFI44L | interferon-induced protein 44-like | 2.00722 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -6.01161 |
| CDC20 | cell division cycle 20 | -5.90126 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.86666 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.91765 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | -4.71187 |
| NUP85 | nucleoporin 85kDa | -4.67859 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -4.65819 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.55786 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.52404 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.5122 |
| ISOC1 | isochorismatase domain containing 1 | -4.49119 |
| COG2 | component of oligomeric golgi complex 2 | -4.48262 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.44764 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -4.34559 |
| DSG2 | desmoglein 2 | -4.28583 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.22848 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.20134 |
| RPIA | ribose 5-phosphate isomerase A | -4.15583 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.13752 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -4.04127 |
| CCDC86 | coiled-coil domain containing 86 | -3.98814 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.98304 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.95037 |
| NCK1 | NCK adaptor protein 1 | -3.91009 |
| THAP11 | THAP domain containing 11 | -3.77809 |
| TRIB3 | tribbles pseudokinase 3 | -3.53256 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -3.45474 |
| CHMP4B | charged multivesicular body protein 4B | -3.41861 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.40651 |
| AHSP | alpha hemoglobin stabilizing protein | -3.11773 |
| NGRN | neugrin, neurite outgrowth associated | -3.01572 |
| ALAS2 | 5'-aminolevulinate synthase 2 | -2.87613 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.82242 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.78029 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | -2.74754 |
| PPOX | protoporphyrinogen oxidase | -2.7342 |
| TLR4 | toll-like receptor 4 | -2.71312 |
| HBG1 | hemoglobin, gamma A | -2.62119 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -2.54708 |
| PEG10 | paternally expressed 10 | -2.51119 |
| EPB42 | erythrocyte membrane protein band 4.2 | -2.50102 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.46488 |
| HBD | hemoglobin, delta | -2.41024 |
| CCNB1 | cyclin B1 | -2.36293 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -2.35251 |
| RGS2 | regulator of G-protein signaling 2 | -2.28451 |
| ZW10 | zw10 kinetochore protein | -2.25999 |
| TMCC2 | transmembrane and coiled-coil domain family 2 | -2.24061 |
| TGFB3 | transforming growth factor, beta 3 | -2.23873 |
| CPNE3 | copine III | -2.16369 |
| DMTN | dematin actin binding protein | -2.15002 |
| NISCH | nischarin | -2.14662 |
| MARCHF8 | membrane associated ring-CH-type finger 8 | -2.06499 |
| XK | X-linked Kx blood group | -2.05103 |
| TRIM58 | tripartite motif containing 58 | -2.03326 |
| SAP30BP | SAP30 binding protein | -2.0327 |
| MKRN1 | makorin ring finger protein 1 | -2.02501 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.0097 |
| TIMELESS | timeless circadian clock | -2.00884 |
