CRCGN014_HEPG2_24H:F11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description adipamide 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN014_HEPG2_24H:F11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 7.51397
MAP7 microtubule-associated protein 7 5.65422
MNAT1 MNAT CDK-activating kinase assembly factor 1 5.39776
C2CD2 C2 calcium-dependent domain containing 2 4.64128
GPER1 G protein-coupled estrogen receptor 1 3.56139
E2F2 E2F transcription factor 2 3.06491
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 2.87597
TBC1D31 TBC1 domain family, member 31 2.81999
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 2.60356
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.41719
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 2.31553
MYLK myosin light chain kinase 2.22378
GSTZ1 glutathione S-transferase zeta 1 2.14172
IFI44L interferon-induced protein 44-like 2.1244
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.04297
NUSAP1 nucleolar and spindle associated protein 1 2.02945

decreased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 -6.88046
HEATR1 HEAT repeat containing 1 -5.56063
LDHD lactate dehydrogenase D -5.00826
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.98124
CDC20 cell division cycle 20 -4.53542
CHMP4B charged multivesicular body protein 4B -3.92253
NGRN neugrin, neurite outgrowth associated -3.75961
SNX11 sorting nexin 11 -2.64314
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.51915
PCNA proliferating cell nuclear antigen -2.43244
FASTKD5 FAST kinase domains 5 -2.42949
ILK integrin-linked kinase -2.24761
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.12332
LOC114841035 uncharacterized LOC114841035 -2.06112