CRCGN014_HEPG2_24H:F12 Gene Set
Genes
36 genes differentially expressed following the CRCGN014_HEPG2_24H:F12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.69103
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
4.02311
|
|
CHN1
|
chimerin 1
|
3.47676
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.1747
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
2.96247
|
|
AXIN1
|
axin 1
|
2.93581
|
|
BLMH
|
bleomycin hydrolase
|
2.89978
|
|
E2F2
|
E2F transcription factor 2
|
2.76632
|
|
SFTPB
|
surfactant protein B
|
2.70855
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.51377
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.46863
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.38193
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.35075
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.32443
|
|
RPL39L
|
ribosomal protein L39-like
|
2.30147
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.23531
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.20547
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.20451
|
|
NUSAP1
|
nucleolar and spindle associated protein 1
|
2.09131
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.01949
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-7.2789
|
|
LDHD
|
lactate dehydrogenase D
|
-6.96275
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-5.78817
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.45934
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.24076
|
|
CCNB2
|
cyclin B2
|
-2.90397
|
|
TES
|
testin LIM domain protein
|
-2.85097
|
|
CD320
|
CD320 molecule
|
-2.84564
|
|
TLR4
|
toll-like receptor 4
|
-2.743
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.7353
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.6735
|
|
ZNF586
|
zinc finger protein 586
|
-2.48702
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.34612
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.26643
|
|
DNM1L
|
dynamin 1-like
|
-2.19786
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.03677
|
