CRCGN014_HEPG2_24H:F13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description telone ii 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

38 genes differentially expressed following the CRCGN014_HEPG2_24H:F13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RPP38 ribonuclease P/MRP 38kDa subunit 4.9289
AMDHD2 amidohydrolase domain containing 2 4.58217
TREM1 triggering receptor expressed on myeloid cells 1 3.63362
MAP7 microtubule-associated protein 7 3.29735
LOC122526780 uncharacterized LOC122526780 3.00148
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.6647
TXNL4B thioredoxin-like 4B 2.63482
NOSIP nitric oxide synthase interacting protein 2.60185
TBC1D31 TBC1 domain family, member 31 2.56207
CHN1 chimerin 1 2.55734
RAB21 RAB21, member RAS oncogene family 2.34657
RXYLT1 ribitol xylosyltransferase 1 2.28658
MYG1 MYG1 exonuclease 2.03144

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -8.74052
TLR4 toll-like receptor 4 -6.23505
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -5.59425
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.47183
DNM1L dynamin 1-like -4.46956
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.26852
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.15243
KDM3A lysine (K)-specific demethylase 3A -4.0634
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.98523
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.94164
DERA deoxyribose-phosphate aldolase (putative) -3.7307
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -3.73035
TRAPPC3 trafficking protein particle complex 3 -3.62387
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.90668
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -2.63654
FBXO7 F-box protein 7 -2.38196
OXA1L oxidase (cytochrome c) assembly 1-like -2.14249
MARCHF5 membrane associated ring-CH-type finger 5 -2.11687
ITGB1BP1 integrin beta 1 binding protein 1 -2.09681
GDF15 growth differentiation factor 15 -2.08867
UNC13D unc-13 homolog D (C. elegans) -2.07377
PARP3 poly (ADP-ribose) polymerase family, member 3 -2.06795
TM9SF2 transmembrane 9 superfamily member 2 -2.04772
FN1 fibronectin 1 -2.01147
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 -2.00233