CRCGN014_HEPG2_24H:F14 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_24H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.95368
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.68774
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.58066
|
|
TXNRD1
|
thioredoxin reductase 1
|
3.36931
|
|
STK10
|
serine/threonine kinase 10
|
3.12455
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.0042
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.86436
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.85088
|
|
STIMATE
|
STIM activating enhancer
|
2.8479
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.79779
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.75259
|
|
AXIN1
|
axin 1
|
2.73569
|
|
IDE
|
insulin-degrading enzyme
|
2.66919
|
|
MYLK
|
myosin light chain kinase
|
2.58372
|
|
EPN2
|
epsin 2
|
2.55713
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.36291
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.23159
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.14612
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.08615
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.04935
|
|
PLA2G4A
|
phospholipase A2, group IVA (cytosolic, calcium-dependent)
|
2.01653
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CD320
|
CD320 molecule
|
-6.47294
|
|
GOLT1B
|
golgi transport 1B
|
-4.59083
|
|
PLK1
|
polo-like kinase 1
|
-3.89217
|
|
SPAG4
|
sperm associated antigen 4
|
-3.75798
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.64189
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.42619
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.36164
|
|
ZNF586
|
zinc finger protein 586
|
-3.25397
|
|
GNAS
|
GNAS complex locus
|
-3.03903
|
|
PEG10
|
paternally expressed 10
|
-2.99216
|
|
LDHD
|
lactate dehydrogenase D
|
-2.93481
|
|
SNX11
|
sorting nexin 11
|
-2.61305
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.3633
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.35035
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.27688
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.23167
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.21391
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.17447
|
|
TES
|
testin LIM domain protein
|
-2.17236
|
|
MTA1
|
metastasis associated 1
|
-2.1066
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.08693
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-2.0789
|
|
VAT1
|
vesicle amine transport 1
|
-2.07451
|
