CRCGN014_HEPG2_24H:F19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-nitroanthranilic acid 40.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN014_HEPG2_24H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CIAO3 cytosolic iron-sulfur assembly component 3 8.01815
GPER1 G protein-coupled estrogen receptor 1 5.10873
MYLK myosin light chain kinase 4.88413
SYNE2 spectrin repeat containing, nuclear envelope 2 4.29963
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 4.11014
LCN2 lipocalin 2 4.10708
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.50744
VAV3 vav 3 guanine nucleotide exchange factor 3.10975
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.93804
KIF20A kinesin family member 20A 2.75643
UBQLN2 ubiquilin 2 2.70551
HEBP1 heme binding protein 1 2.57241
STK10 serine/threonine kinase 10 2.42869
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.36342
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.08538
KRT15 keratin 15, type I 2.00075

decreased expression

Symbol Name Standardized Value
SCAND1 SCAN domain containing 1 -4.44012
MRPS2 mitochondrial ribosomal protein S2 -4.12583
CDC20 cell division cycle 20 -4.0439
UGDH UDP-glucose 6-dehydrogenase -3.75525
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.90943
FGFR4 fibroblast growth factor receptor 4 -2.88529
TLR4 toll-like receptor 4 -2.78837
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.42729
EIF5 eukaryotic translation initiation factor 5 -2.41268
CTSD cathepsin D -2.31937
STAT1 signal transducer and activator of transcription 1, 91kDa -2.14354
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.03808
MORF4L2 mortality factor 4 like 2 -2.02404
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.00382