CRCGN014_HEPG2_24H:G02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description pirinixic-acid 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

389 genes differentially expressed following the CRCGN014_HEPG2_24H:G02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 7.61287
PRR15L proline rich 15-like 6.84746
HOXA10 homeobox A10 6.35525
CXCL2 chemokine (C-X-C motif) ligand 2 5.78203
GARRE1 granule associated Rac and RHOG effector 1 5.0236
GATA3 GATA binding protein 3 4.85563
GSTZ1 glutathione S-transferase zeta 1 4.74156
MAMLD1 mastermind-like domain containing 1 4.55197
BIRC2 baculoviral IAP repeat containing 2 4.53992
CBR3 carbonyl reductase 3 4.50562
E2F2 E2F transcription factor 2 4.5037
MCOLN1 mucolipin 1 4.46978
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 4.34267
TREM1 triggering receptor expressed on myeloid cells 1 4.31533
MYLK myosin light chain kinase 4.30778
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 4.29223
EGF epidermal growth factor 4.27614
TAC4 tachykinin 4 (hemokinin) 4.17034
TATDN2 TatD DNase domain containing 2 4.11212
HLA-DMA major histocompatibility complex, class II, DM alpha 3.97421
UBQLN2 ubiquilin 2 3.92297
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.91962
SYNE2 spectrin repeat containing, nuclear envelope 2 3.81509
PLS1 plastin 1 3.76364
BACE2 beta-site APP-cleaving enzyme 2 3.71174
HOXA10-HOXA9 HOXA10-HOXA9 readthrough 3.67719
MOK MOK protein kinase 3.6608
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.62947
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 3.62845
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.59824
SNAP25 synaptosomal-associated protein, 25kDa 3.56808
ECH1 enoyl CoA hydratase 1, peroxisomal 3.51918
STK10 serine/threonine kinase 10 3.46224
TIAM1 T-cell lymphoma invasion and metastasis 1 3.44612
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.42547
ADRB2 adrenoceptor beta 2, surface 3.42546
CSN1S1 casein alpha s1 3.34879
EPHB2 EPH receptor B2 3.28171
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 3.27387
ACACB acetyl-CoA carboxylase beta 3.21999
ABHD6 abhydrolase domain containing 6 3.20819
ADGRE5 adhesion G protein-coupled receptor E5 3.20088
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.18488
HOXB9 homeobox B9 3.16602
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.14276
CHN1 chimerin 1 3.10649
ALDOC aldolase C, fructose-bisphosphate 3.0914
PPARG peroxisome proliferator-activated receptor gamma 3.08203
L1TD1 LINE-1 type transposase domain containing 1 3.07635
MAGIX MAGI family member, X-linked 2.99884
PIH1D1 PIH1 domain containing 1 2.99442
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.9876
CEP57 centrosomal protein 57kDa 2.98608
ASL argininosuccinate lyase 2.9791
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.95275
CIAO3 cytosolic iron-sulfur assembly component 3 2.94617
BTN1A1 butyrophilin, subfamily 1, member A1 2.89536
CD40 CD40 molecule, TNF receptor superfamily member 5 2.87409
LRRC31 leucine rich repeat containing 31 2.86722
HEBP1 heme binding protein 1 2.77324
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.77255
ASCL2 achaete-scute family bHLH transcription factor 2 2.75601
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.74591
FAM13A family with sequence similarity 13, member A 2.73181
RAB21 RAB21, member RAS oncogene family 2.72955
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 2.7211
CRIPTO3 cripto, EGF-CFC family member 3 2.71873
NR1I2 nuclear receptor subfamily 1, group I, member 2 2.71178
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.70636
CD1D CD1d molecule 2.6996
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 2.68768
TRAM2 translocation associated membrane protein 2 2.67576
TRMT9B tRNA methyltransferase 9B (putative) 2.67529
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.66653
CLCA1 chloride channel accessory 1 2.65779
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.64047
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 2.6316
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.57004
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 2.56683
ZNF273 zinc finger protein 273 2.55217
UTS2 urotensin 2 2.54436
OLFM4 olfactomedin 4 2.53077
LOC100996750 keratin-associated protein 4-7 2.52281
RNFT1 ring finger protein, transmembrane 1 2.51346
APOF apolipoprotein F 2.50997
ICAM2 intercellular adhesion molecule 2 2.50468
NOX1 NADPH oxidase 1 2.50415
ACE2 angiotensin I converting enzyme 2 2.49567
COQ8B coenzyme Q8B 2.4926
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.47484
ACOXL acyl-CoA oxidase-like 2.46946
LDAF1 lipid droplet assembly factor 1 2.46511
ZNF780B zinc finger protein 780B 2.46434
SNRPN small nuclear ribonucleoprotein polypeptide N 2.4631
CFAP68 cilia and flagella associated protein 68 2.4615
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 2.46126
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.43498
EXOC6B exocyst complex component 6B 2.43202
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.42554
TSPYL4 TSPY-like 4 2.42296
ADGRE1 adhesion G protein-coupled receptor E1 2.41231
MBTD1 mbt domain containing 1 2.40866
MROH9 maestro heat-like repeat family member 9 2.40745
ZNF675 zinc finger protein 675 2.40047
ZNF80 zinc finger protein 80 2.39847
ZNF440 zinc finger protein 440 2.38991
CCDC82 coiled-coil domain containing 82 2.3759
RPL8 ribosomal protein L8 2.37522
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 2.36767
SNW1 SNW domain containing 1 2.36522
KRT35 keratin 35, type I 2.36025
PON3 paraoxonase 3 2.35229
OR2B2 olfactory receptor, family 2, subfamily B, member 2 2.34918
DSG1 desmoglein 1 2.34875
DIPK1A divergent protein kinase domain 1A 2.34697
IFNA8 interferon, alpha 8 2.34434
NR3C2 nuclear receptor subfamily 3, group C, member 2 2.34378
ZNF157 zinc finger protein 157 2.34269
USH2A Usher syndrome 2A (autosomal recessive, mild) 2.33884
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.33215
BUD23 BUD23 rRNA methyltransferase and ribosome maturation factor 2.32247
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 2.32012
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2.31955
PRDM13 PR domain containing 13 2.31477
PNLIPRP2 pancreatic lipase-related protein 2 2.31402
POF1B premature ovarian failure, 1B 2.30862
SYCP1 synaptonemal complex protein 1 2.30612
NDNF neuron-derived neurotrophic factor 2.30538
ADPRH ADP-ribosylarginine hydrolase 2.30427
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.30157
QDPR quinoid dihydropteridine reductase 2.30102
FGF16 fibroblast growth factor 16 2.29782
SPATA6L spermatogenesis associated 6-like 2.29565
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.29364
SIM1 single-minded family bHLH transcription factor 1 2.2911
HAVCR1 hepatitis A virus cellular receptor 1 2.29089
OR1A1 olfactory receptor, family 1, subfamily A, member 1 2.29057
MTRF1L mitochondrial translational release factor 1-like 2.29052
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2.28994
LPAR2 lysophosphatidic acid receptor 2 2.28961
ZNF234 zinc finger protein 234 2.28847
GFM1 G elongation factor, mitochondrial 1 2.28565
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 2.2848
FOXE3 forkhead box E3 2.28302
KRTAP9-9 keratin associated protein 9-9 2.28243
EAPP E2F-associated phosphoprotein 2.28017
XDH xanthine dehydrogenase 2.27602
OR7A10 olfactory receptor, family 7, subfamily A, member 10 2.27446
PAQR5 progestin and adipoQ receptor family member V 2.27068
USP53 ubiquitin specific peptidase 53 2.27011
ZNF674 zinc finger protein 674 2.26868
EDDM3A epididymal protein 3A 2.266
GYS2 glycogen synthase 2 (liver) 2.26347
OR2W1 olfactory receptor, family 2, subfamily W, member 1 2.26003
SPO11 SPO11 meiotic protein covalently bound to DSB 2.25732
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.25562
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.2546
CPLX2 complexin 2 2.25088
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.25053
DMTF1 cyclin D binding myb-like transcription factor 1 2.25027
KIF24 kinesin family member 24 2.2494
CDX2 caudal type homeobox 2 2.24918
CASP5 caspase 5, apoptosis-related cysteine peptidase 2.24827
EDDM3B epididymal protein 3B 2.24774
FAM13C family with sequence similarity 13, member C 2.24672
ZNF471 zinc finger protein 471 2.23991
PTK6 protein tyrosine kinase 6 2.23671
ZNF254 zinc finger protein 254 2.23307
LRAT lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) 2.22693
ANKRD7 ankyrin repeat domain 7 2.22495
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.22381
GLP2R glucagon-like peptide 2 receptor 2.22041
ZNF780A zinc finger protein 780A 2.21651
MAGEB3 melanoma antigen family B3 2.21264
KRTAP1-3 keratin associated protein 1-3 2.21264
NSF N-ethylmaleimide-sensitive factor 2.21087
PCDHB8 protocadherin beta 8 2.20959
RAD21L1 RAD21-like 1 (S. pombe) 2.20868
CCDC88C coiled-coil domain containing 88C 2.20051
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 2.19156
GLRA3 glycine receptor, alpha 3 2.18801
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.184
CD36 CD36 molecule (thrombospondin receptor) 2.18376
NOX3 NADPH oxidase 3 2.17195
NPHP1 nephronophthisis 1 (juvenile) 2.16885
ZNF682 zinc finger protein 682 2.16845
ITK IL2-inducible T-cell kinase 2.16666
TAS2R9 taste receptor, type 2, member 9 2.16366
TADA2A transcriptional adaptor 2A 2.16258
ZNF660-ZNF197 ZNF660-ZNF197 readthrough 2.16235
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 2.16112
FAM135A family with sequence similarity 135, member A 2.15733
MAGEA11 melanoma antigen family A11 2.15723
CABP5 calcium binding protein 5 2.1569
ADGRE3 adhesion G protein-coupled receptor E3 2.15486
MTERF3 mitochondrial transcription termination factor 3 2.15414
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.15272
TLL1 tolloid-like 1 2.15125
PPP4R4 protein phosphatase 4, regulatory subunit 4 2.14993
ZBTB33 zinc finger and BTB domain containing 33 2.14982
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 2.14272
THAP9 THAP domain containing 9 2.14149
CCDC144A coiled-coil domain containing 144A 2.13422
SCRN3 secernin 3 2.13043
POU1F1 POU class 1 homeobox 1 2.12931
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 2.12923
IRF5 interferon regulatory factor 5 2.12912
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.12875
EPHA3 EPH receptor A3 2.12676
EHF ets homologous factor 2.12642
CMKLR2 chemerin chemokine-like receptor 2 2.12368
ZNF749 zinc finger protein 749 2.12368
CNTN6 contactin 6 2.12037
DEFA5 defensin, alpha 5, Paneth cell-specific 2.1201
NLRP1 NLR family, pyrin domain containing 1 2.11915
CASS4 Cas scaffolding protein family member 4 2.11816
GP6 glycoprotein VI (platelet) 2.11368
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.1124
RAVER2 ribonucleoprotein, PTB-binding 2 2.11098
SHOX short stature homeobox 2.11081
CCR7 chemokine (C-C motif) receptor 7 2.10812
RFPL1 ret finger protein-like 1 2.10751
GTPBP10 GTP-binding protein 10 (putative) 2.10651
ZNF407 zinc finger protein 407 2.10506
SH2B2 SH2B adaptor protein 2 2.1032
VN1R1 vomeronasal 1 receptor 1 2.1027
PAPPA pregnancy-associated plasma protein A, pappalysin 1 2.10241
CXCL11 chemokine (C-X-C motif) ligand 11 2.10194
IFNA2 interferon, alpha 2 2.10107
FEV FEV (ETS oncogene family) 2.10099
ZNF391 zinc finger protein 391 2.09959
HRH4 histamine receptor H4 2.09784
QPCT glutaminyl-peptide cyclotransferase 2.09729
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 2.09689
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.09422
MAGEC3 melanoma antigen family C3 2.09396
RXYLT1 ribitol xylosyltransferase 1 2.09334
PIGR polymeric immunoglobulin receptor 2.0889
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.08672
DEFB126 defensin, beta 126 2.08569
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.08566
ADAM7 ADAM metallopeptidase domain 7 2.08452
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.08363
ARSL arylsulfatase L 2.08301
IFNA5 interferon, alpha 5 2.08286
SLC25A30 solute carrier family 25, member 30 2.07875
FPGS folylpolyglutamate synthase 2.07847
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.07751
KLF8 Kruppel-like factor 8 2.07731
TEX12 testis expressed 12 2.07725
IL12B interleukin 12B 2.07683
ZNF442 zinc finger protein 442 2.07065
ATOH1 atonal homolog 1 (Drosophila) 2.06945
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 2.06861
TLR6 toll-like receptor 6 2.06421
TH tyrosine hydroxylase 2.06225
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.05791
DGKE diacylglycerol kinase, epsilon 64kDa 2.0538
KRTAP1-1 keratin associated protein 1-1 2.05378
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 2.05257
ZNF81 zinc finger protein 81 2.05159
KERA keratocan 2.04956
TUBAL3 tubulin, alpha-like 3 2.04769
SPINK4 serine peptidase inhibitor, Kazal type 4 2.04731
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 2.04663
STMN2 stathmin 2 2.04613
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 2.04403
GSC2 goosecoid homeobox 2 2.04243
JCHAIN joining chain of multimeric IgA and IgM 2.04172
MLNR motilin receptor 2.04164
PRSS58 protease, serine, 58 2.03613
HOXA7 homeobox A7 2.03398
IMPG1 interphotoreceptor matrix proteoglycan 1 2.03128
CNOT4 CCR4-NOT transcription complex, subunit 4 2.02965
MTMR7 myotubularin related protein 7 2.02916
HCRTR1 hypocretin (orexin) receptor 1 2.02786
SCN11A sodium channel, voltage gated, type XI alpha subunit 2.02622
ZIC3 Zic family member 3 2.02312
GCM2 glial cells missing homolog 2 (Drosophila) 2.02273
FABP1 fatty acid binding protein 1, liver 2.02253
ZNF302 zinc finger protein 302 2.02008
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.01773
MARF1 meiosis regulator and mRNA stability factor 1 2.01727
SEMG2 semenogelin II 2.01698
MSH4 mutS homolog 4 2.01638
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 2.01496
FCN1 ficolin (collagen/fibrinogen domain containing) 1 2.01367
MTNR1A melatonin receptor 1A 2.01217
CSK c-src tyrosine kinase 2.01212
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D 2.0107
CCL27 chemokine (C-C motif) ligand 27 2.01021
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 2.01
KIAA0408 KIAA0408 2.00927
METTL16 methyltransferase like 16 2.00899
LATS1 large tumor suppressor kinase 1 2.00575
CMA1 chymase 1, mast cell 2.00452
MYLK3 myosin light chain kinase 3 2.00362
CRYBA2 crystallin, beta A2 2.00361
TRIM58 tripartite motif containing 58 2.00278
OR2F2 olfactory receptor, family 2, subfamily F, member 2 2.00256
ACHE acetylcholinesterase (Yt blood group) 2.00188
PADI4 peptidyl arginine deiminase, type IV 2.00117
FFAR2 free fatty acid receptor 2 2.00075

decreased expression

Symbol Name Standardized Value
FBXL12 F-box and leucine-rich repeat protein 12 -5.33259
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.03568
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.67477
ARID5B AT rich interactive domain 5B (MRF1-like) -4.35126
ANKRD10 ankyrin repeat domain 10 -4.12094
SLC35F2 solute carrier family 35, member F2 -4.00174
FAIM Fas apoptotic inhibitory molecule -3.99968
CCDC86 coiled-coil domain containing 86 -3.96448
COG4 component of oligomeric golgi complex 4 -3.96301
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.88177
FOS FBJ murine osteosarcoma viral oncogene homolog -3.8661
MRPS16 mitochondrial ribosomal protein S16 -3.82685
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -3.70282
TM9SF3 transmembrane 9 superfamily member 3 -3.50263
NCK1 NCK adaptor protein 1 -3.33952
CCNB1 cyclin B1 -3.32277
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.31759
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.23131
VDAC1 voltage-dependent anion channel 1 -3.04257
FASTKD5 FAST kinase domains 5 -2.98401
CUTC cutC copper transporter -2.92213
MOSPD1 motile sperm domain containing 1 -2.92037
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.89463
TOR1A torsin family 1, member A (torsin A) -2.85299
GTPBP8 GTP-binding protein 8 (putative) -2.75248
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.74556
NUP85 nucleoporin 85kDa -2.68936
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.6883
NCK2 NCK adaptor protein 2 -2.67691
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa -2.63283
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.62856
ZMIZ1 zinc finger, MIZ-type containing 1 -2.60616
STAMBP STAM binding protein -2.5819
ANO10 anoctamin 10 -2.5688
CUEDC2 CUE domain containing 2 -2.5546
ETV5 ets variant 5 -2.5543
PRKCQ protein kinase C, theta -2.53773
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.50596
CCDC92 coiled-coil domain containing 92 -2.4751
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor -2.46349
NISCH nischarin -2.45679
CTNND1 catenin (cadherin-associated protein), delta 1 -2.44823
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.43835
TOE1 target of EGR1, member 1 (nuclear) -2.42194
UCK2 uridine-cytidine kinase 2 -2.42169
MTFR1 mitochondrial fission regulator 1 -2.40399
SPDEF SAM pointed domain containing ETS transcription factor -2.40324
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -2.39578
PAK1IP1 PAK1 interacting protein 1 -2.36419
STIMATE STIM activating enhancer -2.3641
FARS2 phenylalanyl-tRNA synthetase 2, mitochondrial -2.36358
PRCC papillary renal cell carcinoma (translocation-associated) -2.34016
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.33628
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -2.304
MFF mitochondrial fission factor -2.29962
TRIM8 tripartite motif containing 8 -2.29672
FZD1 frizzled class receptor 1 -2.29181
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.27918
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -2.26148
LMO4 LIM domain only 4 -2.2613
RAI14 retinoic acid induced 14 -2.25757
PARG poly (ADP-ribose) glycohydrolase -2.23509
MSRA methionine sulfoxide reductase A -2.22539
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.1734
ZDHHC6 zinc finger, DHHC-type containing 6 -2.17151
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.16945
MRPL58 mitochondrial ribosomal protein L58 -2.16256
MRPS18A mitochondrial ribosomal protein S18A -2.13876
TBPL1 TBP-like 1 -2.1245
ASCC2 activating signal cointegrator 1 complex subunit 2 -2.12039
STAP2 signal transducing adaptor family member 2 -2.11773
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -2.11451
GABPB1 GA binding protein transcription factor, beta subunit 1 -2.10611
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) -2.09982
PYDC1 PYD (pyrin domain) containing 1 -2.08758
TMEM94 transmembrane protein 94 -2.08381
TWNK twinkle mtDNA helicase -2.08243
DPH2 DPH2 homolog (S. cerevisiae) -2.07862
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.06523
MEA1 male-enhanced antigen 1 -2.05578
TOMM34 translocase of outer mitochondrial membrane 34 -2.04985
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.04863
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.02321
CYB561D2 cytochrome b561 family, member D2 -2.01781
NR1H2 nuclear receptor subfamily 1, group H, member 2 -2.01094
STAU2 staufen double-stranded RNA binding protein 2 -2.00417