CRCGN014_HEPG2_24H:G03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-rosaniline.hcl 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

1068 genes differentially expressed following the CRCGN014_HEPG2_24H:G03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ANO1 anoctamin 1, calcium activated chloride channel 10.0
INPP1 inositol polyphosphate-1-phosphatase 10.0
FHL2 four and a half LIM domains 2 8.29517
CAB39 calcium binding protein 39 8.10272
ANKRD10 ankyrin repeat domain 10 7.81476
LCN2 lipocalin 2 7.78885
STX1A syntaxin 1A (brain) 7.5946
FOSL1 FOS-like antigen 1 7.54192
SHB Src homology 2 domain containing adaptor protein B 7.51211
GFOD1 glucose-fructose oxidoreductase domain containing 1 7.40098
ZFP36 ZFP36 ring finger protein 7.3211
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 7.14821
KIFBP kinesin family binding protein 7.12312
MICALL1 MICAL-like 1 7.0086
TXNRD1 thioredoxin reductase 1 6.91296
KLHL21 kelch-like family member 21 6.8744
MYC v-myc avian myelocytomatosis viral oncogene homolog 6.83028
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 6.68921
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.44238
GFPT1 glutamine--fructose-6-phosphate transaminase 1 6.33343
IER3 immediate early response 3 6.20901
BZW2 basic leucine zipper and W2 domains 2 6.06793
CDPF1 cysteine-rich, DPF motif domain containing 1 5.96732
TESK1 testis-specific kinase 1 5.91044
CASC3 cancer susceptibility candidate 3 5.7762
DDIT4 DNA-damage-inducible transcript 4 5.72688
TIMP2 TIMP metallopeptidase inhibitor 2 5.57875
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 5.48549
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 5.35573
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 5.23149
PTPN12 protein tyrosine phosphatase, non-receptor type 12 5.13422
IL4R interleukin 4 receptor 5.11329
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 5.08191
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 4.85773
STK10 serine/threonine kinase 10 4.74326
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 4.67886
PHKA1 phosphorylase kinase, alpha 1 (muscle) 4.678
NPC1 Niemann-Pick disease, type C1 4.67687
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 4.65047
FOXJ3 forkhead box J3 4.64631
CCDC92 coiled-coil domain containing 92 4.61785
IGFBP3 insulin-like growth factor binding protein 3 4.61545
TOMM34 translocase of outer mitochondrial membrane 34 4.52167
MVP major vault protein 4.5079
SQSTM1 sequestosome 1 4.50588
ACOT9 acyl-CoA thioesterase 9 4.45809
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.43706
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 4.41511
SLC35F2 solute carrier family 35, member F2 4.41314
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.30592
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 4.28696
EGR1 early growth response 1 4.28576
CYCS cytochrome c, somatic 4.27048
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.26122
MAP7D1 MAP7 domain containing 1 4.18531
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.14079
NCK2 NCK adaptor protein 2 4.13122
RFC2 replication factor C (activator 1) 2, 40kDa 4.04447
TES testin LIM domain protein 3.92099
EPN2 epsin 2 3.87916
TICAM1 toll-like receptor adaptor molecule 1 3.86548
PPARD peroxisome proliferator-activated receptor delta 3.84644
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 3.8443
RUSC2 RUN and SH3 domain containing 2 3.81083
SMAD3 SMAD family member 3 3.80785
TRIB1 tribbles pseudokinase 1 3.80634
TRIM13 tripartite motif containing 13 3.7779
PRAF2 PRA1 domain family, member 2 3.7567
PLK3 polo-like kinase 3 3.7558
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 3.74076
LARP6 La ribonucleoprotein domain family, member 6 3.73212
KHDC4 KH domain containing 4, pre-mRNA splicing factor 3.68066
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.65894
SOCS2 suppressor of cytokine signaling 2 3.65241
ZMIZ1 zinc finger, MIZ-type containing 1 3.64746
DSG2 desmoglein 2 3.63704
PDGFA platelet-derived growth factor alpha polypeptide 3.62852
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 3.61736
H2BC21 H2B clustered histone 21 3.56595
BCL7B B-cell CLL/lymphoma 7B 3.56229
GRB10 growth factor receptor-bound protein 10 3.53652
TBPL1 TBP-like 1 3.5302
CDK7 cyclin-dependent kinase 7 3.51995
NUP58 nucleoporin 58 3.49504
CLIP2 CAP-GLY domain containing linker protein 2 3.45731
MYH9 myosin, heavy chain 9, non-muscle 3.44916
FOXO4 forkhead box O4 3.44659
CHEK1 checkpoint kinase 1 3.3988
MACF1 microtubule-actin crosslinking factor 1 3.36386
YARS1 tyrosyl-tRNA synthetase 1 3.36155
RHOG ras homolog family member G 3.35518
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 3.34594
POMZP3 POM121 and ZP3 fusion 3.31787
MSN moesin 3.30438
TP53BP2 tumor protein p53 binding protein 2 3.29914
KLHL4 kelch-like family member 4 3.27817
JOSD1 Josephin domain containing 1 3.27337
ATF6 activating transcription factor 6 3.27027
MAP7 microtubule-associated protein 7 3.26395
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.26089
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.25925
TGFB1I1 transforming growth factor beta 1 induced transcript 1 3.221
MBNL1 muscleblind-like splicing regulator 1 3.21408
KDM5A lysine (K)-specific demethylase 5A 3.20212
EGFR epidermal growth factor receptor 3.18912
ZYX zyxin 3.18861
ZBTB10 zinc finger and BTB domain containing 10 3.18446
SLC38A2 solute carrier family 38, member 2 3.16813
MYLK myosin light chain kinase 3.16801
RALB v-ral simian leukemia viral oncogene homolog B 3.1398
ANKRD12 ankyrin repeat domain 12 3.13751
CAMTA2 calmodulin binding transcription activator 2 3.12632
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.12394
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 3.12264
PTPRC protein tyrosine phosphatase, receptor type, C 3.1161
CCNA1 cyclin A1 3.10954
EIF3D eukaryotic translation initiation factor 3, subunit D 3.10681
TLN1 talin 1 3.09755
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 3.09329
FASTKD5 FAST kinase domains 5 3.08827
HLA-DRA major histocompatibility complex, class II, DR alpha 3.06151
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.04322
PTPN14 protein tyrosine phosphatase, non-receptor type 14 3.03904
GOLT1A golgi transport 1A 3.0365
SH3GLB1 SH3-domain GRB2-like endophilin B1 3.02669
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 3.02592
FAM168B family with sequence similarity 168, member B 3.00927
ALAS1 5'-aminolevulinate synthase 1 3.00624
LYN LYN proto-oncogene, Src family tyrosine kinase 3.00388
TERF2IP telomeric repeat binding factor 2, interacting protein 2.98252
LOC128125814 uncharacterized LOC128125814 2.96601
EIF4H eukaryotic translation initiation factor 4H 2.96206
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.95254
PTPRK protein tyrosine phosphatase, receptor type, K 2.95039
ABHD4 abhydrolase domain containing 4 2.94527
TRIM8 tripartite motif containing 8 2.92652
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.92533
ITPRID2 ITPR interacting domain containing 2 2.92452
SMNDC1 survival motor neuron domain containing 1 2.91624
DUSP8 dual specificity phosphatase 8 2.91397
BPHL biphenyl hydrolase-like (serine hydrolase) 2.90615
CSNK1E casein kinase 1, epsilon 2.89121
ATOSB atos homolog B 2.87483
ASCC3 activating signal cointegrator 1 complex subunit 3 2.86767
CCNJ cyclin J 2.8641
TNIP1 TNFAIP3 interacting protein 1 2.85481
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 2.84464
ARHGAP22 Rho GTPase activating protein 22 2.84039
RGS2 regulator of G-protein signaling 2 2.83844
TSC22D3 TSC22 domain family, member 3 2.8372
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.83645
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.83438
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 2.83296
LRP10 low density lipoprotein receptor-related protein 10 2.82697
PLSCR3 phospholipid scramblase 3 2.81854
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 2.81785
BMAL2 basic helix-loop-helix ARNT like 2 2.81103
AIRIM AFG2 interacting ribosome maturation factor 2.81009
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.80479
CYTH2 cytohesin 2 2.80142
PDE8A phosphodiesterase 8A 2.80112
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.79689
AFF4 AF4/FMR2 family, member 4 2.7943
CLDN4 claudin 4 2.78322
ZBTB6 zinc finger and BTB domain containing 6 2.78226
ANXA11 annexin A11 2.76988
SARS1 seryl-tRNA synthetase 1 2.76325
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 2.75666
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.7552
CRISP2 cysteine-rich secretory protein 2 2.74882
MGLL monoglyceride lipase 2.74553
PRKCD protein kinase C, delta 2.72335
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.71713
ELL2 elongation factor, RNA polymerase II, 2 2.71277
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 2.70812
MARK4 MAP/microtubule affinity-regulating kinase 4 2.70682
JUN jun proto-oncogene 2.70297
KITLG KIT ligand 2.6939
E2F2 E2F transcription factor 2 2.69285
C2CD2L C2CD2-like 2.68884
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 2.68311
KPNA4 karyopherin alpha 4 (importin alpha 3) 2.67554
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.67424
TBC1D15 TBC1 domain family, member 15 2.67024
EPS8 epidermal growth factor receptor pathway substrate 8 2.6631
NPDC1 neural proliferation, differentiation and control, 1 2.65745
LORICRIN loricrin cornified envelope precursor protein 2.65207
BAZ1B bromodomain adjacent to zinc finger domain, 1B 2.64333
SYNJ2 synaptojanin 2 2.6325
HSPA1A heat shock 70kDa protein 1A 2.62431
GHITM growth hormone inducible transmembrane protein 2.6225
BIRC2 baculoviral IAP repeat containing 2 2.62224
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.61862
RIN3 Ras and Rab interactor 3 2.61399
TRIP10 thyroid hormone receptor interactor 10 2.61128
ERBIN erbb2 interacting protein 2.60944
CSRNP2 cysteine-serine-rich nuclear protein 2 2.60794
WLS wntless Wnt ligand secretion mediator 2.60251
MAGIX MAGI family member, X-linked 2.60229
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.6019
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.59662
GARS1 glycyl-tRNA synthetase 1 2.59413
ANGPT2 angiopoietin 2 2.59343
TMEM184B transmembrane protein 184B 2.59168
BICD2 bicaudal D homolog 2 (Drosophila) 2.57961
ATF4 activating transcription factor 4 2.5785
TAS2R10 taste receptor, type 2, member 10 2.57689
SERINC1 serine incorporator 1 2.57505
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.57164
FEM1C fem-1 homolog c (C. elegans) 2.57016
CAMLG calcium modulating ligand 2.56944
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.56774
LMBR1L limb development membrane protein 1-like 2.56634
KIAA0408 KIAA0408 2.56336
GADD45A growth arrest and DNA-damage-inducible, alpha 2.55318
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.55039
PPP1R26 protein phosphatase 1, regulatory subunit 26 2.55022
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.5494
OCLN occludin 2.54798
SNX6 sorting nexin 6 2.54378
FJX1 four jointed box 1 (Drosophila) 2.54158
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.53893
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.5374
LRRC8E leucine rich repeat containing 8 family, member E 2.53448
FMNL3 formin-like 3 2.52966
GOLT1B golgi transport 1B 2.52964
S100A7 S100 calcium binding protein A7 2.52441
MAPK8 mitogen-activated protein kinase 8 2.51631
RAB9A RAB9A, member RAS oncogene family 2.51101
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like 2.50526
ANKLE2 ankyrin repeat and LEM domain containing 2 2.50493
ITCH itchy E3 ubiquitin protein ligase 2.50393
SH2B3 SH2B adaptor protein 3 2.50115
TFE3 transcription factor binding to IGHM enhancer 3 2.49851
CD9 CD9 molecule 2.49751
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.49671
ETV6 ets variant 6 2.4941
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.4926
CDCP1 CUB domain containing protein 1 2.48843
SUN2 Sad1 and UNC84 domain containing 2 2.48463
GPC1 glypican 1 2.48317
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) 2.4789
H2BC11 H2B clustered histone 11 2.47845
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 2.47765
KIF13B kinesin family member 13B 2.47655
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.47247
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 2.47131
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.46799
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 2.46603
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 2.46208
H2BC17 H2B clustered histone 17 2.45668
IL26 interleukin 26 2.45423
NIBAN1 niban apoptosis regulator 1 2.445
PFDN2 prefoldin subunit 2 2.44474
R3HCC1L R3H domain and coiled-coil containing 1-like 2.43733
PLPP6 phospholipid phosphatase 6 2.43153
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 2.43148
CORO2B coronin, actin binding protein, 2B 2.43048
USP3 ubiquitin specific peptidase 3 2.42988
AGO2 argonaute RISC catalytic component 2 2.42971
TEX10 testis expressed 10 2.42925
WIPF1 WAS/WASL interacting protein family, member 1 2.4282
PDZK1IP1 PDZK1 interacting protein 1 2.41708
HSPA1B heat shock 70kDa protein 1B 2.41705
AHNAK AHNAK nucleoprotein 2.41682
CA2 carbonic anhydrase II 2.4146
ZNF141 zinc finger protein 141 2.41096
YY1AP1 YY1 associated protein 1 2.40989
RGCC regulator of cell cycle 2.40944
ADORA2B adenosine A2b receptor 2.40913
BRD1 bromodomain containing 1 2.4086
CLK3 CDC-like kinase 3 2.40377
ESM1 endothelial cell-specific molecule 1 2.40266
MCOLN3 mucolipin 3 2.40211
ASCC1 activating signal cointegrator 1 complex subunit 1 2.3992
C2CD2 C2 calcium-dependent domain containing 2 2.39233
HDAC5 histone deacetylase 5 2.39232
NCOA3 nuclear receptor coactivator 3 2.39149
CTNND1 catenin (cadherin-associated protein), delta 1 2.38976
RPAP3 RNA polymerase II associated protein 3 2.3889
PALM2AKAP2 PALM2 and AKAP2 fusion 2.38833
MIER2 mesoderm induction early response 1, family member 2 2.38777
DNASE2B deoxyribonuclease II beta 2.38658
VAT1 vesicle amine transport 1 2.38372
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 2.37562
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae) 2.37443
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 2.3636
CDK17 cyclin-dependent kinase 17 2.36253
RAP1GAP RAP1 GTPase activating protein 2.36253
LHFPL2 lipoma HMGIC fusion partner-like 2 2.35682
HDAC7 histone deacetylase 7 2.35511
NR1D2 nuclear receptor subfamily 1, group D, member 2 2.35189
AKAP12 A kinase (PRKA) anchor protein 12 2.35164
SRFBP1 serum response factor binding protein 1 2.35092
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.3474
BANP BTG3 associated nuclear protein 2.34649
EVA1B eva-1 homolog B (C. elegans) 2.34629
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 2.34519
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.34046
MYO1D myosin ID 2.33951
ZCCHC8 zinc finger, CCHC domain containing 8 2.33781
VTA1 vesicle (multivesicular body) trafficking 1 2.33747
STEEP1 STING1 ER exit protein 1 2.3364
FXYD5 FXYD domain containing ion transport regulator 5 2.33593
PRICKLE3 prickle homolog 3 (Drosophila) 2.33353
CALML5 calmodulin-like 5 2.33276
RTN4 reticulon 4 2.33111
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) 2.32872
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.32817
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 2.32808
LIF leukemia inhibitory factor 2.32457
SVIL supervillin 2.32107
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 2.31982
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.3195
ZNF804A zinc finger protein 804A 2.31499
LSR lipolysis stimulated lipoprotein receptor 2.31446
PSPC1 paraspeckle component 1 2.31327
CSDC2 cold shock domain containing C2, RNA binding 2.31233
TUT7 terminal uridylyl transferase 7 2.31125
RIOK3 RIO kinase 3 2.31051
BRSK2 BR serine/threonine kinase 2 2.31021
PEA15 phosphoprotein enriched in astrocytes 15 2.3097
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 2.3083
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.30674
BAIAP2 BAI1-associated protein 2 2.3062
PER1 period circadian clock 1 2.30326
PSEN1 presenilin 1 2.30291
TENT4A terminal nucleotidyltransferase 4A 2.30057
CIAO3 cytosolic iron-sulfur assembly component 3 2.29791
EDDM3A epididymal protein 3A 2.29776
SNAI1 snail family zinc finger 1 2.29424
CCSER2 coiled-coil serine-rich protein 2 2.294
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.29288
OSBPL3 oxysterol binding protein-like 3 2.28958
ST14 suppression of tumorigenicity 14 (colon carcinoma) 2.28855
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.28669
RTN2 reticulon 2 2.28665
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 2.28643
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 2.28436
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.28382
ATP5F1B ATP synthase F1 subunit beta 2.28316
DENND4C DENN/MADD domain containing 4C 2.27966
SMR3A submaxillary gland androgen regulated protein 3A 2.27648
PPARG peroxisome proliferator-activated receptor gamma 2.27538
H2BC6 H2B clustered histone 6 2.27194
NHLH2 nescient helix loop helix 2 2.26911
CRABP2 cellular retinoic acid binding protein 2 2.26655
NCALD neurocalcin delta 2.26213
CDR2L cerebellar degeneration-related protein 2-like 2.25794
BCL10 B-cell CLL/lymphoma 10 2.25741
NCOA4 nuclear receptor coactivator 4 2.25616
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.25196
ENOX1 ecto-NOX disulfide-thiol exchanger 1 2.25158
RTCA RNA 3'-terminal phosphate cyclase 2.2512
BRDT bromodomain, testis-specific 2.24777
KAT6A K(lysine) acetyltransferase 6A 2.24776
STX5 syntaxin 5 2.24717
TMEM204 transmembrane protein 204 2.24685
PDE5A phosphodiesterase 5A, cGMP-specific 2.24601
GPER1 G protein-coupled estrogen receptor 1 2.24601
SPAG9 sperm associated antigen 9 2.24501
SNAI2 snail family zinc finger 2 2.24476
SUSD6 sushi domain containing 6 2.24447
TOR4A torsin family 4, member A 2.24394
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 2.24144
PRKCI protein kinase C, iota 2.23871
CUL4B cullin 4B 2.2354
HCFC2 host cell factor C2 2.23114
SNX16 sorting nexin 16 2.22838
HPSE heparanase 2.2264
DRD1 dopamine receptor D1 2.22294
KLK6 kallikrein-related peptidase 6 2.22291
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.22175
GPR87 G protein-coupled receptor 87 2.21856
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.21779
TMEM144 transmembrane protein 144 2.21519
GPKOW G patch domain and KOW motifs 2.21353
SMC5 structural maintenance of chromosomes 5 2.21338
IER2 immediate early response 2 2.20935
TAGLN2 transgelin 2 2.20873
EIF5A2 eukaryotic translation initiation factor 5A2 2.20868
IL37 interleukin 37 2.2075
PAQR5 progestin and adipoQ receptor family member V 2.20649
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 2.20553
INHA inhibin, alpha 2.20493
CIZ1 CDKN1A interacting zinc finger protein 1 2.20351
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.20211
LNPEP leucyl/cystinyl aminopeptidase 2.20125
FBXW11 F-box and WD repeat domain containing 11 2.19981
ZNF225 zinc finger protein 225 2.19902
PRKCQ protein kinase C, theta 2.1946
RB1 retinoblastoma 1 2.19219
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.19035
ZNF227 zinc finger protein 227 2.18885
POPDC3 popeye domain containing 3 2.18716
CAMSAP1 calmodulin regulated spectrin-associated protein 1 2.18709
ABI1 abl-interactor 1 2.1858
RNF115 ring finger protein 115 2.18325
HIC1 hypermethylated in cancer 1 2.18283
POM121C POM121 transmembrane nucleoporin C 2.18144
MAP1B microtubule-associated protein 1B 2.17833
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 2.17796
RAB33A RAB33A, member RAS oncogene family 2.17595
MEF2D myocyte enhancer factor 2D 2.17502
HTRA1 HtrA serine peptidase 1 2.17462
BAG2 BCL2-associated athanogene 2 2.17334
TUBB6 tubulin, beta 6 class V 2.17307
SOX9 SRY (sex determining region Y)-box 9 2.17188
PADI2 peptidyl arginine deiminase, type II 2.17161
PEX26 peroxisomal biogenesis factor 26 2.16636
RGS10 regulator of G-protein signaling 10 2.16515
ZNF410 zinc finger protein 410 2.16489
MLNR motilin receptor 2.16404
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.16355
FKRP fukutin related protein 2.16303
LPAR2 lysophosphatidic acid receptor 2 2.1613
RFTN1 raftlin, lipid raft linker 1 2.15842
CHD1 chromodomain helicase DNA binding protein 1 2.15692
CFLAR CASP8 and FADD-like apoptosis regulator 2.15616
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 2.1552
NUAK2 NUAK family, SNF1-like kinase, 2 2.15385
H2BC3 H2B clustered histone 3 2.15258
LY6D lymphocyte antigen 6 complex, locus D 2.15168
PHF1 PHD finger protein 1 2.14854
ATF3 activating transcription factor 3 2.14619
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 2.13913
ANXA8L1 annexin A8-like 1 2.13884
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.13827
RAP1A RAP1A, member of RAS oncogene family 2.13681
IL23A interleukin 23, alpha subunit p19 2.13662
CSRNP3 cysteine-serine-rich nuclear protein 3 2.13647
PLAUR plasminogen activator, urokinase receptor 2.13507
GABPB1 GA binding protein transcription factor, beta subunit 1 2.13211
SPAG4 sperm associated antigen 4 2.13105
NT5E 5'-nucleotidase, ecto (CD73) 2.12843
CREM cAMP responsive element modulator 2.12757
MYO5A myosin VA (heavy chain 12, myoxin) 2.12291
SERINC3 serine incorporator 3 2.12049
TSC1 tuberous sclerosis 1 2.11946
RGS20 regulator of G-protein signaling 20 2.11931
KLK8 kallikrein-related peptidase 8 2.11609
PLCL1 phospholipase C-like 1 2.11541
YAF2 YY1 associated factor 2 2.11442
RASAL2 RAS protein activator like 2 2.11438
NACA2 nascent polypeptide-associated complex alpha subunit 2 2.11396
MINK1 misshapen-like kinase 1 2.11379
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.11346
RHOC ras homolog family member C 2.11314
PELI1 pellino E3 ubiquitin protein ligase 1 2.11153
HSF2 heat shock transcription factor 2 2.11019
LIN37 lin-37 DREAM MuvB core complex component 2.11
SH2B2 SH2B adaptor protein 2 2.1091
SEC14L1 SEC14-like 1 (S. cerevisiae) 2.10468
ZBTB33 zinc finger and BTB domain containing 33 2.10323
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.10235
HOXD3 homeobox D3 2.10215
DGKB diacylglycerol kinase, beta 90kDa 2.09685
KDM6B lysine (K)-specific demethylase 6B 2.09545
PORCN porcupine homolog (Drosophila) 2.09483
FOXD1 forkhead box D1 2.09416
H2BC14 H2B clustered histone 14 2.09376
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.09254
ZNF549 zinc finger protein 549 2.08989
LRFN4 leucine rich repeat and fibronectin type III domain containing 4 2.08754
KISS1 KiSS-1 metastasis-suppressor 2.08561
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 2.08428
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 2.08276
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.0825
SF3B2 splicing factor 3b, subunit 2, 145kDa 2.08244
PCDHGA11 protocadherin gamma subfamily A, 11 2.08153
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 2.08061
CLEC5A C-type lectin domain family 5, member A 2.07696
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 2.07616
ZFP69B ZFP69 zinc finger protein B 2.07497
FOXC1 forkhead box C1 2.07435
HOMER2 homer scaffolding protein 2 2.07435
IL19 interleukin 19 2.07336
MYO6 myosin VI 2.07154
QSER1 glutamine and serine rich 1 2.06803
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.0615
NOP2 NOP2 nucleolar protein 2.06115
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 2.059
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.05808
LZTS3 leucine zipper, putative tumor suppressor family member 3 2.05782
PARP6 poly (ADP-ribose) polymerase family, member 6 2.0566
FABP2 fatty acid binding protein 2, intestinal 2.05617
SLC49A3 solute carrier family 49 member 3 2.05565
HAUS6 HAUS augmin-like complex, subunit 6 2.05465
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 2.05426
B2M beta-2-microglobulin 2.05364
RNF32 ring finger protein 32 2.05316
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 2.0527
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.05205
STX4 syntaxin 4 2.05194
CARMIL1 capping protein regulator and myosin 1 linker 1 2.05107
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 2.04951
LOC124900275 extensin-like 2.0492
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.04892
PLPPR1 phospholipid phosphatase related 1 2.04876
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.04811
HMGA1 high mobility group AT-hook 1 2.04515
CLCN4 chloride channel, voltage-sensitive 4 2.04472
NEUROG2 neurogenin 2 2.04429
JHY junctional cadherin complex regulator 2.04405
EHF ets homologous factor 2.04378
KNTC1 kinetochore associated 1 2.04318
TNIP2 TNFAIP3 interacting protein 2 2.04193
ZNF574 zinc finger protein 574 2.03906
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.03855
ZBTB7C zinc finger and BTB domain containing 7C 2.03616
KLF7 Kruppel-like factor 7 (ubiquitous) 2.03615
DAZL deleted in azoospermia-like 2.03522
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 2.03505
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.03451
RAB3B RAB3B, member RAS oncogene family 2.03395
CLDN10 claudin 10 2.03113
CATSPERB catsper channel auxiliary subunit beta 2.03055
ADAM7 ADAM metallopeptidase domain 7 2.0274
ZNF674 zinc finger protein 674 2.02603
ZNF780B zinc finger protein 780B 2.02463
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.0222
OSMR oncostatin M receptor 2.02204
MAPK12 mitogen-activated protein kinase 12 2.02161
PURG purine-rich element binding protein G 2.02071
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.02013
ITGB5 integrin, beta 5 2.01996
CNIH3 cornichon family AMPA receptor auxiliary protein 3 2.01983
AATF apoptosis antagonizing transcription factor 2.01717
GTF2E2 general transcription factor IIE, polypeptide 2, beta 34kDa 2.01717
HABP4 hyaluronan binding protein 4 2.01586
CAVIN1 caveolae associated protein 1 2.01566
STX3 syntaxin 3 2.01488
LCOR ligand dependent nuclear receptor corepressor 2.01447
GDI1 GDP dissociation inhibitor 1 2.01183
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 2.01172
IFRD1 interferon-related developmental regulator 1 2.00872
LIPF lipase, gastric 2.00867
TIMP1 TIMP metallopeptidase inhibitor 1 2.00866
IER5 immediate early response 5 2.00814
DOHH deoxyhypusine hydroxylase/monooxygenase 2.0078
BAMBI BMP and activin membrane-bound inhibitor 2.00739
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.00703
UTP25 UTP25 small subunit processome component 2.00354
PXDC1 PX domain containing 1 2.00269
ZBTB43 zinc finger and BTB domain containing 43 2.00189
CLTA clathrin, light chain A 2.00179
STMN4 stathmin-like 4 2.00178
SH3BP4 SH3-domain binding protein 4 2.00167
DNM1L dynamin 1-like 2.00091
EIF3A eukaryotic translation initiation factor 3, subunit A 2.00012

decreased expression

Symbol Name Standardized Value
B4GAT1 beta-1,4-glucuronyltransferase 1 -10.0
CD320 CD320 molecule -9.44239
PARP1 poly (ADP-ribose) polymerase 1 -8.79469
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -8.7841
TCTN1 tectonic family member 1 -8.46758
TARBP1 TAR (HIV-1) RNA binding protein 1 -8.02457
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -7.79721
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -7.75295
PCCB propionyl CoA carboxylase, beta polypeptide -7.7433
SCAND1 SCAN domain containing 1 -7.71835
RPS4Y1 ribosomal protein S4, Y-linked 1 -7.62034
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -7.58813
MRPL12 mitochondrial ribosomal protein L12 -7.28892
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -7.03504
PGM1 phosphoglucomutase 1 -6.87517
COG7 component of oligomeric golgi complex 7 -6.69883
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -6.67165
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -6.63828
NIPSNAP1 nipsnap homolog 1 (C. elegans) -6.22506
ALDOC aldolase C, fructose-bisphosphate -6.16472
ADI1 acireductone dioxygenase 1 -6.01585
FGFR4 fibroblast growth factor receptor 4 -5.98848
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -5.71234
HMGA2 high mobility group AT-hook 2 -5.68974
MLEC malectin -5.6629
PGAM4 phosphoglycerate mutase family member 4 -5.604
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -5.41383
CETN3 centrin, EF-hand protein, 3 -5.33381
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -5.28654
MYCBP MYC binding protein -5.23114
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -5.20557
BLCAP bladder cancer associated protein -5.19735
CCNA2 cyclin A2 -5.19096
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -5.14755
ICAM3 intercellular adhesion molecule 3 -5.08284
ECH1 enoyl CoA hydratase 1, peroxisomal -5.07747
LBR lamin B receptor -5.00267
DERA deoxyribose-phosphate aldolase (putative) -4.97758
PSRC1 proline/serine-rich coiled-coil 1 -4.90912
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -4.84171
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.80497
RPA3 replication protein A3, 14kDa -4.79605
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -4.79157
LDHD lactate dehydrogenase D -4.76386
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.76281
LAGE3 L antigen family, member 3 -4.74797
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.7057
PROS1 protein S (alpha) -4.68335
SKIC2 SKI2 subunit of superkiller complex -4.66214
NLRP2B NLR family pyrin domain containing 2B -4.65604
TRAP1 TNF receptor-associated protein 1 -4.63287
RPIA ribose 5-phosphate isomerase A -4.63258
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -4.58226
TMEM97 transmembrane protein 97 -4.57839
GAA glucosidase, alpha; acid -4.54311
INTS3 integrator complex subunit 3 -4.53347
TEDC2 tubulin epsilon and delta complex 2 -4.4689
UBL5 ubiquitin-like 5 -4.46423
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -4.4613
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -4.419
C2CD5 C2 calcium-dependent domain containing 5 -4.36769
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.25688
MRPS16 mitochondrial ribosomal protein S16 -4.2561
PRCP prolylcarboxypeptidase (angiotensinase C) -4.15044
GCDH glutaryl-CoA dehydrogenase -4.12386
CBR1 carbonyl reductase 1 -4.12337
C5 complement component 5 -4.11184
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -4.1017
SKIC8 SKI8 subunit of superkiller complex -4.09914
STAMBP STAM binding protein -4.04259
TOP2A topoisomerase (DNA) II alpha 170kDa -4.02394
CTSL cathepsin L -4.00553
PAGR1 PAXIP1 associated glutamate-rich protein 1 -3.9719
HADH hydroxyacyl-CoA dehydrogenase -3.96611
TMEM109 transmembrane protein 109 -3.95998
NT5DC2 5'-nucleotidase domain containing 2 -3.95683
NUCB2 nucleobindin 2 -3.95656
CDK1 cyclin-dependent kinase 1 -3.95297
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.94444
SCGB1D1 secretoglobin, family 1D, member 1 -3.93973
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -3.93904
KLHDC2 kelch domain containing 2 -3.93618
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.93547
CRYZ crystallin, zeta (quinone reductase) -3.91049
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -3.87582
TWF2 twinfilin actin binding protein 2 -3.83787
STAT1 signal transducer and activator of transcription 1, 91kDa -3.83146
MRPL19 mitochondrial ribosomal protein L19 -3.82673
RUVBL1 RuvB-like AAA ATPase 1 -3.82045
UBE2C ubiquitin-conjugating enzyme E2C -3.7898
TSPAN6 tetraspanin 6 -3.78323
THAP11 THAP domain containing 11 -3.78052
HAT1 histone acetyltransferase 1 -3.77561
COG4 component of oligomeric golgi complex 4 -3.76711
CETN2 centrin, EF-hand protein, 2 -3.76189
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -3.75949
PLK1 polo-like kinase 1 -3.74665
FKBP3 FK506 binding protein 3, 25kDa -3.72072
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.70242
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.70063
SCCPDH saccharopine dehydrogenase (putative) -3.69991
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -3.67569
MRPL11 mitochondrial ribosomal protein L11 -3.66452
EED embryonic ectoderm development -3.66057
MELK maternal embryonic leucine zipper kinase -3.58983
MIS18A MIS18 kinetochore protein A -3.5852
TLR4 toll-like receptor 4 -3.56342
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.53275
HEBP1 heme binding protein 1 -3.52619
CRELD2 cysteine-rich with EGF-like domains 2 -3.48057
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -3.47432
PDIA6 protein disulfide isomerase family A, member 6 -3.451
AURKB aurora kinase B -3.41633
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.41446
SNX17 sorting nexin 17 -3.40845
QTRT1 queuine tRNA-ribosyltransferase 1 -3.40057
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -3.38697
USP6NL USP6 N-terminal like -3.38501
NME4 NME/NM23 nucleoside diphosphate kinase 4 -3.38339
ETFB electron-transfer-flavoprotein, beta polypeptide -3.37001
AMDHD2 amidohydrolase domain containing 2 -3.36825
DTYMK deoxythymidylate kinase (thymidylate kinase) -3.35618
SDF2L1 stromal cell-derived factor 2-like 1 -3.32822
CENPX centromere protein X -3.32137
BCL7C B-cell CLL/lymphoma 7C -3.31336
SLC35B1 solute carrier family 35, member B1 -3.31285
RMDN1 regulator of microtubule dynamics 1 -3.28295
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.27356
LMAN2L lectin, mannose-binding 2-like -3.26212
GTF2A2 general transcription factor IIA, 2, 12kDa -3.26047
GATD3 glutamine amidotransferase class 1 domain containing 3 -3.24556
CDC20 cell division cycle 20 -3.23661
MRPL17 mitochondrial ribosomal protein L17 -3.23541
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -3.21311
GLRX5 glutaredoxin 5 -3.20711
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -3.1948
TMEM14A transmembrane protein 14A -3.16839
RBKS ribokinase -3.16835
BIRC5 baculoviral IAP repeat containing 5 -3.16262
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -3.16012
PGRMC1 progesterone receptor membrane component 1 -3.15808
ASF1B anti-silencing function 1B histone chaperone -3.14732
LRRC61 leucine rich repeat containing 61 -3.13841
COA3 cytochrome c oxidase assembly factor 3 -3.13302
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.13056
ACAA1 acetyl-CoA acyltransferase 1 -3.12754
BLMH bleomycin hydrolase -3.10004
CDK4 cyclin-dependent kinase 4 -3.09283
DCK deoxycytidine kinase -3.07759
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -3.07704
ATP5MC1 ATP synthase membrane subunit c locus 1 -3.07135
DYNLT3 dynein, light chain, Tctex-type 3 -3.06253
TLCD3A TLC domain containing 3A -3.04752
CHEK2 checkpoint kinase 2 -3.04209
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.0307
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.02586
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.02582
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -3.02529
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.02074
TFDP1 transcription factor Dp-1 -3.00687
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -3.00465
MRPL30 mitochondrial ribosomal protein L30 -3.00454
CSRP2 cysteine and glycine-rich protein 2 -2.99295
AMT aminomethyltransferase -2.98321
TBC1D10C TBC1 domain family, member 10C -2.98225
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.9705
BST2 bone marrow stromal cell antigen 2 -2.96877
PHKB phosphorylase kinase, beta -2.94461
CPNE3 copine III -2.9371
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -2.93605
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.93572
GLT8D1 glycosyltransferase 8 domain containing 1 -2.92717
ABHD14A abhydrolase domain containing 14A -2.91807
TMEM50B transmembrane protein 50B -2.91427
LYRM1 LYR motif containing 1 -2.91307
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.91034
SEPHS1 selenophosphate synthetase 1 -2.90682
RWDD3 RWD domain containing 3 -2.90391
SIVA1 SIVA1, apoptosis-inducing factor -2.89769
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -2.88629
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast) -2.88574
ATRAID all-trans retinoic acid-induced differentiation factor -2.88025
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -2.86988
SNX11 sorting nexin 11 -2.8692
ZNF443 zinc finger protein 443 -2.85433
ANAPC15 anaphase promoting complex subunit 15 -2.85226
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -2.84935
EMC9 ER membrane protein complex subunit 9 -2.8451
PDIA4 protein disulfide isomerase family A, member 4 -2.83771
ATP5IF1 ATP synthase inhibitory factor subunit 1 -2.83737
TMEM106C transmembrane protein 106C -2.83734
NUP107 nucleoporin 107kDa -2.82645
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa -2.82145
BOLA2B bolA family member 2B -2.82074
CENPS-CORT CENPS-CORT readthrough -2.81742
VRK1 vaccinia related kinase 1 -2.8167
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.81463
ANXA7 annexin A7 -2.81332
MRPL46 mitochondrial ribosomal protein L46 -2.81244
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -2.80488
TSEN34 TSEN34 tRNA splicing endonuclease subunit -2.80476
DEXI Dexi homolog (mouse) -2.80118
SCML2 sex comb on midleg-like 2 (Drosophila) -2.79818
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.79798
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa -2.78488
MSRB1 methionine sulfoxide reductase B1 -2.77492
NENF neudesin neurotrophic factor -2.76172
ZW10 zw10 kinetochore protein -2.75132
FBXL12 F-box and leucine-rich repeat protein 12 -2.74689
MYL9 myosin, light chain 9, regulatory -2.74495
KIFC1 kinesin family member C1 -2.74058
HAGH hydroxyacylglutathione hydrolase -2.73519
ARFIP2 ADP-ribosylation factor interacting protein 2 -2.73038
PLA2G2D phospholipase A2, group IID -2.7287
PARN poly(A)-specific ribonuclease -2.72751
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.72093
SH3D19 SH3 domain containing 19 -2.72069
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.71919
LY86 lymphocyte antigen 86 -2.71139
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.71008
TRIP13 thyroid hormone receptor interactor 13 -2.7056
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.70531
PDIA5 protein disulfide isomerase family A, member 5 -2.69961
PECR peroxisomal trans-2-enoyl-CoA reductase -2.69804
TECR trans-2,3-enoyl-CoA reductase -2.69766
TSEN2 TSEN2 tRNA splicing endonuclease subunit -2.6948
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.69198
CSTPP1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 -2.68877
ATP5MF ATP synthase membrane subunit f -2.68577
CCDC90B coiled-coil domain containing 90B -2.68447
POLR2G polymerase (RNA) II (DNA directed) polypeptide G -2.67911
RCL1 RNA terminal phosphate cyclase-like 1 -2.67509
BABAM1 BRISC and BRCA1 A complex member 1 -2.67241
APOM apolipoprotein M -2.67178
MRS2 MRS2 magnesium transporter -2.66809
TM7SF2 transmembrane 7 superfamily member 2 -2.6576
LYRM9 LYR motif containing 9 -2.64806
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -2.64711
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.63642
TOR3A torsin family 3, member A -2.6338
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -2.63035
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.62864
ZDHHC24 zinc finger, DHHC-type containing 24 -2.62626
ITGB1BP1 integrin beta 1 binding protein 1 -2.62479
SNRPF small nuclear ribonucleoprotein polypeptide F -2.62363
GLYAT glycine-N-acyltransferase -2.61454
HBQ1 hemoglobin, theta 1 -2.61279
CENPM centromere protein M -2.6125
TMX1 thioredoxin-related transmembrane protein 1 -2.61012
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 -2.60058
AKAP8 A kinase (PRKA) anchor protein 8 -2.60021
NNT nicotinamide nucleotide transhydrogenase -2.59572
SCUBE2 signal peptide, CUB domain, EGF-like 2 -2.59503
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 -2.59356
CCS copper chaperone for superoxide dismutase -2.59208
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -2.59038
KHK ketohexokinase (fructokinase) -2.58977
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.58767
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.58721
MRPL34 mitochondrial ribosomal protein L34 -2.58444
WDR70 WD repeat domain 70 -2.58401
PYGL phosphorylase, glycogen, liver -2.58267
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.58117
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.56916
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -2.56806
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.55879
DUT deoxyuridine triphosphatase -2.55707
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.55258
ATP5ME ATP synthase membrane subunit e -2.54828
NTHL1 nth endonuclease III-like 1 (E. coli) -2.54568
PRMT1 protein arginine methyltransferase 1 -2.54412
NFIL3 nuclear factor, interleukin 3 regulated -2.54224
CBR4 carbonyl reductase 4 -2.54079
SOAT2 sterol O-acyltransferase 2 -2.53802
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.53733
FAM174C family with sequence similarity 174 member C -2.53088
TCTN3 tectonic family member 3 -2.5301
FZD7 frizzled class receptor 7 -2.52918
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 -2.52249
BANF1 barrier to autointegration factor 1 -2.5219
EDAR ectodysplasin A receptor -2.51218
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -2.51199
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.51181
PFKL phosphofructokinase, liver -2.50708
GCAT glycine C-acetyltransferase -2.50283
CCDC51 coiled-coil domain containing 51 -2.5006
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 -2.4983
CA5A carbonic anhydrase VA, mitochondrial -2.49627
DHRS11 dehydrogenase/reductase (SDR family) member 11 -2.49602
SIRT3 sirtuin 3 -2.49339
CCNB2 cyclin B2 -2.49231
MAT2A methionine adenosyltransferase II, alpha -2.49097
PPA2 pyrophosphatase (inorganic) 2 -2.4825
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -2.479
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -2.47575
TMEM126B transmembrane protein 126B -2.47239
ORC6 origin recognition complex, subunit 6 -2.46959
PTTG1 pituitary tumor-transforming 1 -2.45935
TRAPPC4 trafficking protein particle complex 4 -2.45517
SAMM50 SAMM50 sorting and assembly machinery component -2.45181
CARHSP1 calcium regulated heat stable protein 1, 24kDa -2.44981
RNF43 ring finger protein 43 -2.44409
GEMIN6 gem (nuclear organelle) associated protein 6 -2.44032
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.43201
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 -2.42848
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.42759
TMEM160 transmembrane protein 160 -2.42635
IGFLR1 IGF-like family receptor 1 -2.42096
MSMO1 methylsterol monooxygenase 1 -2.41764
OCEL1 occludin/ELL domain containing 1 -2.4134
MTMR4 myotubularin related protein 4 -2.41174
EIPR1 EARP complex and GARP complex interacting protein 1 -2.40347
OXLD1 oxidoreductase-like domain containing 1 -2.39965
RECQL4 RecQ protein-like 4 -2.39741
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.39701
NME3 NME/NM23 nucleoside diphosphate kinase 3 -2.39585
MRPL23 mitochondrial ribosomal protein L23 -2.39368
UNC119B unc-119 homolog B (C. elegans) -2.39243
BAHCC1 BAH domain and coiled-coil containing 1 -2.39223
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) -2.39211
NHP2 NHP2 ribonucleoprotein -2.39057
RAD54L RAD54-like (S. cerevisiae) -2.38849
FABP1 fatty acid binding protein 1, liver -2.38799
BMP4 bone morphogenetic protein 4 -2.38794
SPPL2A signal peptide peptidase like 2A -2.38765
MSRB2 methionine sulfoxide reductase B2 -2.38554
PCNA proliferating cell nuclear antigen -2.37653
CDK5 cyclin-dependent kinase 5 -2.37622
TMEM135 transmembrane protein 135 -2.37514
DHCR7 7-dehydrocholesterol reductase -2.37346
TMEM177 transmembrane protein 177 -2.37266
RUVBL2 RuvB-like AAA ATPase 2 -2.37105
TRMT5 tRNA methyltransferase 5 -2.37013
NME1 NME/NM23 nucleoside diphosphate kinase 1 -2.36976
NR1H3 nuclear receptor subfamily 1, group H, member 3 -2.36922
SORD sorbitol dehydrogenase -2.36384
DHRS1 dehydrogenase/reductase (SDR family) member 1 -2.36375
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.36323
UQCR11 ubiquinol-cytochrome c reductase, complex III subunit XI -2.36295
GALNS galactosamine (N-acetyl)-6-sulfatase -2.35674
NDUFC2 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa -2.35647
ATF7IP2 activating transcription factor 7 interacting protein 2 -2.35634
HMBS hydroxymethylbilane synthase -2.35357
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 -2.35294
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.34615
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.34548
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase -2.34502
FN3KRP fructosamine 3 kinase related protein -2.34146
ZDHHC4 zinc finger, DHHC-type containing 4 -2.34107
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -2.34013
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.33777
CCDC86 coiled-coil domain containing 86 -2.3374
ATOX1 antioxidant 1 copper chaperone -2.33672
ERLIN2 ER lipid raft associated 2 -2.3366
SRSF3 serine/arginine-rich splicing factor 3 -2.3346
SOD1 superoxide dismutase 1, soluble -2.33391
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -2.32911
GLUL glutamate-ammonia ligase -2.32772
IL33 interleukin 33 -2.32641
COQ3 coenzyme Q3 methyltransferase -2.32498
KIF22 kinesin family member 22 -2.32329
SNF8 SNF8, ESCRT-II complex subunit -2.32308
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.32259
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -2.31938
WDR77 WD repeat domain 77 -2.31579
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -2.31354
AAMP angio-associated, migratory cell protein -2.3012
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -2.29845
AHCY adenosylhomocysteinase -2.29605
RIDA reactive intermediate imine deaminase A homolog -2.29584
MKS1 Meckel syndrome, type 1 -2.29316
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 -2.29125
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -2.29021
POLD2 polymerase (DNA directed), delta 2, accessory subunit -2.28698
ABAT 4-aminobutyrate aminotransferase -2.27934
NCAPD2 non-SMC condensin I complex, subunit D2 -2.27762
EIF5 eukaryotic translation initiation factor 5 -2.27503
ICAM1 intercellular adhesion molecule 1 -2.2738
ZNF83 zinc finger protein 83 -2.27361
HYOU1 hypoxia up-regulated 1 -2.2666
SHFL shiftless antiviral inhibitor of ribosomal frameshifting -2.26436
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.26293
SCARB1 scavenger receptor class B, member 1 -2.26231
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.26207
SPAG16 sperm associated antigen 16 -2.26052
TFB1M transcription factor B1, mitochondrial -2.25943
GTPBP3 GTP binding protein 3 (mitochondrial) -2.25868
ANOS1 anosmin 1 -2.25636
THAP7 THAP domain containing 7 -2.25493
REX1BD required for excision 1-B domain containing -2.25493
GYG2 glycogenin 2 -2.25363
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 -2.25226
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 -2.25108
ECHDC2 enoyl CoA hydratase domain containing 2 -2.25041
HMGB3 high mobility group box 3 -2.2487
TSPAN13 tetraspanin 13 -2.24795
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae) -2.24647
WASF3 WAS protein family, member 3 -2.24479
TK1 thymidine kinase 1, soluble -2.24249
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.24039
THOC6 THO complex 6 -2.23898
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 -2.23891
FUS FUS RNA binding protein -2.23616
GYS1 glycogen synthase 1 (muscle) -2.23435
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.22942
UNG uracil-DNA glycosylase -2.22936
HIBCH 3-hydroxyisobutyryl-CoA hydrolase -2.22163
MYH10 myosin, heavy chain 10, non-muscle -2.22089
NPY neuropeptide Y -2.22022
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.2181
SPIN2B spindlin family, member 2B -2.21675
LOC124907782 dual specificity protein phosphatase 22 -2.21658
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.21433
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -2.21189
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.21113
NISCH nischarin -2.20373
NEK4 NIMA-related kinase 4 -2.20282
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.19861
GAMT guanidinoacetate N-methyltransferase -2.19633
CD99 CD99 molecule -2.19559
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.19265
ACOD1 aconitate decarboxylase 1 -2.19163
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa -2.18975
GBP1 guanylate binding protein 1, interferon-inducible -2.18536
FANCI Fanconi anemia, complementation group I -2.18286
TMEM9B TMEM9 domain family, member B -2.18056
PNPO pyridoxamine 5'-phosphate oxidase -2.17971
GCA grancalcin, EF-hand calcium binding protein -2.17564
CYBC1 cytochrome b-245 chaperone 1 -2.17543
GPC3 glypican 3 -2.17501
DNAAF2 dynein, axonemal, assembly factor 2 -2.17374
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.16872
RNPS1 RNA binding protein S1, serine-rich domain -2.16792
TPMT thiopurine S-methyltransferase -2.16788
H2AX H2A.X variant histone -2.16611
STMN1 stathmin 1 -2.16536
NAAA N-acylethanolamine acid amidase -2.16086
ACOT13 acyl-CoA thioesterase 13 -2.15811
GALK1 galactokinase 1 -2.15203
CRTAP cartilage associated protein -2.15171
UROS uroporphyrinogen III synthase -2.15006
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.14976
SPDEF SAM pointed domain containing ETS transcription factor -2.14907
DCXR dicarbonyl/L-xylulose reductase -2.14745
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -2.14641
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.1415
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.14147
NTS neurotensin -2.13926
TTC31 tetratricopeptide repeat domain 31 -2.13306
ARF5 ADP-ribosylation factor 5 -2.1301
HSPE1 heat shock 10kDa protein 1 -2.12381
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 -2.12274
CPNE1 copine I -2.1215
HSPB2 heat shock 27kDa protein 2 -2.12055
GNG10 guanine nucleotide binding protein (G protein), gamma 10 -2.11938
CALML4 calmodulin-like 4 -2.11785
ERG28 ergosterol biosynthesis 28 homolog -2.11628
MTTP microsomal triglyceride transfer protein -2.11218
QDPR quinoid dihydropteridine reductase -2.11155
CXCL14 chemokine (C-X-C motif) ligand 14 -2.11096
KPTN kaptin (actin binding protein) -2.10728
TP53RK TP53 regulating kinase -2.10441
RBM14-RBM4 RBM14-RBM4 readthrough -2.10433
NKG7 natural killer cell granule protein 7 -2.10419
CCNF cyclin F -2.10101
FIBP fibroblast growth factor (acidic) intracellular binding protein -2.10002
SLC38A10 solute carrier family 38, member 10 -2.09881
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.09877
KDM1A lysine (K)-specific demethylase 1A -2.09692
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.0961
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 -2.09494
AGBL5 ATP/GTP binding protein-like 5 -2.09282
SMCO4 single-pass membrane protein with coiled-coil domains 4 -2.09246
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.09203
ADISSP adipose secreted signaling protein -2.08983
SLIRP SRA stem-loop interacting RNA binding protein -2.08776
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.08192
MTARC1 mitochondrial amidoxime reducing component 1 -2.08107
KIF15 kinesin family member 15 -2.08026
MAGED4B melanoma antigen family D4B -2.07885
PEPD peptidase D -2.07521
APRT adenine phosphoribosyltransferase -2.07497
NIT2 nitrilase family, member 2 -2.07317
IGSF1 immunoglobulin superfamily, member 1 -2.07072
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -2.06955
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -2.06901
BOLA1 bolA family member 1 -2.06699
CKLF-CMTM1 CKLF-CMTM1 readthrough -2.06599
MANF mesencephalic astrocyte-derived neurotrophic factor -2.06227
MRPL4 mitochondrial ribosomal protein L4 -2.0612
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.05946
PEBP1 phosphatidylethanolamine binding protein 1 -2.0588
KDM8 lysine (K)-specific demethylase 8 -2.05764
GFUS GDP-L-fucose synthase -2.0571
PIMREG PICALM interacting mitotic regulator -2.05435
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -2.04872
CALCB calcitonin-related polypeptide beta -2.0465
TMEM14B transmembrane protein 14B -2.04436
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.04055
CZIB CXXC motif containing zinc binding protein -2.03914
KIF4A kinesin family member 4A -2.03901
GGCX gamma-glutamyl carboxylase -2.03784
ISOC2 isochorismatase domain containing 2 -2.03257
GTF2H5 general transcription factor IIH, polypeptide 5 -2.03187
RBX1 ring-box 1, E3 ubiquitin protein ligase -2.03106
PDF peptide deformylase (mitochondrial) -2.0291
ZNF274 zinc finger protein 274 -2.02806
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.02493
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.02321
CENPA centromere protein A -2.01955
ACKR3 atypical chemokine receptor 3 -2.01944
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -2.01824
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.01421
C4BPA complement component 4 binding protein, alpha -2.00959
NUP210 nucleoporin 210kDa -2.00917
ELAC2 elaC ribonuclease Z 2 -2.00509
MGST2 microsomal glutathione S-transferase 2 -2.00113
AKAP7 A kinase (PRKA) anchor protein 7 -2.00064