CRCGN014_HEPG2_24H:G06 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_24H:G06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
4.98005
|
|
LCN2
|
lipocalin 2
|
4.92308
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.74964
|
|
STK10
|
serine/threonine kinase 10
|
4.64572
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
3.35294
|
|
IQGAP1
|
IQ motif containing GTPase activating protein 1
|
3.3422
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.90707
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.90454
|
|
AXIN1
|
axin 1
|
2.87115
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.47679
|
|
SATB1
|
SATB homeobox 1
|
2.42733
|
|
STXBP2
|
syntaxin binding protein 2
|
2.27767
|
|
LRP10
|
low density lipoprotein receptor-related protein 10
|
2.24701
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.10312
|
|
KLHDC8A
|
kelch domain containing 8A
|
2.09738
|
|
UGCG
|
UDP-glucose ceramide glucosyltransferase
|
2.09409
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCDC86
|
coiled-coil domain containing 86
|
-6.07363
|
|
TLR4
|
toll-like receptor 4
|
-6.04735
|
|
CDC20
|
cell division cycle 20
|
-4.96244
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.82462
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.12385
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.90567
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.78902
|
|
LDHD
|
lactate dehydrogenase D
|
-3.60618
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.26452
|
|
CCNB2
|
cyclin B2
|
-3.00095
|
|
GNAS
|
GNAS complex locus
|
-2.9925
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.87439
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.41343
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.39567
|
|
MYF5
|
myogenic factor 5
|
-2.34738
|
|
PEG10
|
paternally expressed 10
|
-2.32367
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.16537
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-2.11971
|
|
RBMS3
|
RNA binding motif, single stranded interacting protein 3
|
-2.0753
|
