CRCGN014_HEPG2_24H:G07 Gene Set
Genes
40 genes differentially expressed following the CRCGN014_HEPG2_24H:G07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.89859
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
4.27639
|
|
JADE2
|
jade family PHD finger 2
|
3.76972
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.52807
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.45344
|
|
EPHB2
|
EPH receptor B2
|
3.4427
|
|
MYLK
|
myosin light chain kinase
|
3.39904
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.27222
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.18721
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
3.07958
|
|
NOTCH1
|
notch 1
|
3.00056
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.53645
|
|
UBQLN2
|
ubiquilin 2
|
2.4671
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.36589
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.35227
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.29683
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.16854
|
|
FZD7
|
frizzled class receptor 7
|
2.10019
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.30861
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-6.29955
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-5.71854
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.74639
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.56668
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.50079
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.45889
|
|
PEG10
|
paternally expressed 10
|
-3.12502
|
|
PLK1
|
polo-like kinase 1
|
-3.07993
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.86727
|
|
CDC20
|
cell division cycle 20
|
-2.69412
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.68969
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.68492
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.60147
|
|
CCNB2
|
cyclin B2
|
-2.49928
|
|
GDF15
|
growth differentiation factor 15
|
-2.28513
|
|
RNF167
|
ring finger protein 167
|
-2.23119
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.17066
|
|
DDX19B
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
|
-2.04666
|
|
EGF
|
epidermal growth factor
|
-2.04046
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.02413
|
|
GNAS
|
GNAS complex locus
|
-2.00014
|
