CRCGN014_HEPG2_24H:G10 Gene Set
Genes
29 genes differentially expressed following the CRCGN014_HEPG2_24H:G10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
7.79655
|
|
EAPP
|
E2F-associated phosphoprotein
|
4.76569
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.62376
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
4.61997
|
|
EVL
|
Enah/Vasp-like
|
4.53334
|
|
CHN1
|
chimerin 1
|
4.51291
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
4.18707
|
|
ZNF589
|
zinc finger protein 589
|
3.95768
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.69981
|
|
EPN2
|
epsin 2
|
3.02811
|
|
GPATCH8
|
G patch domain containing 8
|
2.85247
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
2.75462
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.67529
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.59663
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.39712
|
|
CDK4
|
cyclin-dependent kinase 4
|
2.23317
|
|
MOK
|
MOK protein kinase
|
2.22713
|
|
EPHA3
|
EPH receptor A3
|
2.19906
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.3948
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-5.05275
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.8799
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.77975
|
|
CCNB2
|
cyclin B2
|
-3.14485
|
|
RNF167
|
ring finger protein 167
|
-2.69845
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.4907
|
|
LDHD
|
lactate dehydrogenase D
|
-2.39835
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.3902
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.34299
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.18741
|
