CRCGN014_HEPG2_24H:G11 Gene Set
Genes
32 genes differentially expressed following the CRCGN014_HEPG2_24H:G11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
8.78529
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
5.36244
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.91835
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.12094
|
|
UBQLN2
|
ubiquilin 2
|
3.633
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.01818
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.72582
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.65354
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
2.51703
|
|
CCNF
|
cyclin F
|
2.50072
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.22146
|
|
COL9A3
|
collagen, type IX, alpha 3
|
2.14757
|
|
IFI44L
|
interferon-induced protein 44-like
|
2.1363
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.07324
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.07255
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.03185
|
|
FOXJ3
|
forkhead box J3
|
2.02449
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-8.63444
|
|
LDHD
|
lactate dehydrogenase D
|
-6.09971
|
|
LAP3
|
leucine aminopeptidase 3
|
-5.51868
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.65272
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.66293
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.5108
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.44476
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.43425
|
|
AHSP
|
alpha hemoglobin stabilizing protein
|
-2.3823
|
|
ALPK1
|
alpha-kinase 1
|
-2.32024
|
|
SLC7A7
|
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
|
-2.14464
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.12881
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
-2.08265
|
|
RHCE
|
Rh blood group, CcEe antigens
|
-2.065
|
|
GYPB
|
glycophorin B (MNS blood group)
|
-2.02021
|
