CRCGN014_HEPG2_24H:G12 Gene Set
Genes
38 genes differentially expressed following the CRCGN014_HEPG2_24H:G12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.18607
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
4.94784
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.63054
|
|
CBR3
|
carbonyl reductase 3
|
4.26065
|
|
STK10
|
serine/threonine kinase 10
|
3.88229
|
|
EPHA3
|
EPH receptor A3
|
3.85522
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.60352
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.31837
|
|
PRKCH
|
protein kinase C, eta
|
2.98606
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.98221
|
|
CCNA1
|
cyclin A1
|
2.49518
|
|
TSLIG3A
|
tRNA splicing ligase complex subunit 3A
|
2.42906
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.40029
|
|
CHEK2
|
checkpoint kinase 2
|
2.36762
|
|
KIF20A
|
kinesin family member 20A
|
2.25232
|
|
VGLL4
|
vestigial-like family member 4
|
2.16138
|
|
CHN1
|
chimerin 1
|
2.08564
|
|
MYBL2
|
v-myb avian myeloblastosis viral oncogene homolog-like 2
|
2.0827
|
|
JADE2
|
jade family PHD finger 2
|
2.06661
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.02307
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-9.23723
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.35636
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.95353
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.91195
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-4.72569
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.40349
|
|
LDHD
|
lactate dehydrogenase D
|
-4.40139
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.23136
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.30069
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.94986
|
|
MTA1
|
metastasis associated 1
|
-2.78255
|
|
RNF167
|
ring finger protein 167
|
-2.61738
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.36026
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.33115
|
|
CAMTA2
|
calmodulin binding transcription activator 2
|
-2.23554
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.14601
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.09766
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.0506
|
