CRCGN014_HEPG2_24H:G14 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_24H:G14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
6.43343
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
4.0912
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.4601
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.4207
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.3116
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.2956
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.23717
|
|
STIMATE
|
STIM activating enhancer
|
3.2341
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.16347
|
|
UBQLN2
|
ubiquilin 2
|
3.0727
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.07203
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.95449
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.72787
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.68268
|
|
MAP7
|
microtubule-associated protein 7
|
2.64189
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.46983
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.38528
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.35577
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.3411
|
|
ZNF589
|
zinc finger protein 589
|
2.17477
|
|
JADE2
|
jade family PHD finger 2
|
2.07853
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.05978
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.59213
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-6.5266
|
|
COG4
|
component of oligomeric golgi complex 4
|
-4.00333
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.69477
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-3.6319
|
|
GDF15
|
growth differentiation factor 15
|
-3.33333
|
|
CDC20
|
cell division cycle 20
|
-3.31003
|
|
CCNB2
|
cyclin B2
|
-3.2961
|
|
SLC35B1
|
solute carrier family 35, member B1
|
-3.24173
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.23083
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.17117
|
|
CD320
|
CD320 molecule
|
-3.12017
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-2.9662
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.88303
|
|
LDHD
|
lactate dehydrogenase D
|
-2.8399
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.7343
|
|
NUP85
|
nucleoporin 85kDa
|
-2.6972
|
|
RAI14
|
retinoic acid induced 14
|
-2.6932
|
|
SNX11
|
sorting nexin 11
|
-2.20022
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.12343
|
|
TLR4
|
toll-like receptor 4
|
-2.10147
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.08041
|
