CRCGN014_HEPG2_24H:G16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triamcinolone 20.09 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

40 genes differentially expressed following the CRCGN014_HEPG2_24H:G16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHMP6 charged multivesicular body protein 6 5.97168
KIFBP kinesin family binding protein 4.13487
CIAO3 cytosolic iron-sulfur assembly component 3 3.45173
LCN2 lipocalin 2 3.44791
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.44422
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 3.28447
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.27107
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.92414
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.81803
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.75865
STIMATE STIM activating enhancer 2.73159
RPP38 ribonuclease P/MRP 38kDa subunit 2.64445
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.62005
HOXA10 homeobox A10 2.50599
SCRN1 secernin 1 2.34469
DIPK1A divergent protein kinase domain 1A 2.33133
DDIT4 DNA-damage-inducible transcript 4 2.07106
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.06568
BIRC2 baculoviral IAP repeat containing 2 2.02328
EXOSC4 exosome component 4 2.01847

decreased expression

Symbol Name Standardized Value
ZNF586 zinc finger protein 586 -4.50506
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.37352
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.74628
KDM3A lysine (K)-specific demethylase 3A -3.69287
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.58296
UGDH UDP-glucose 6-dehydrogenase -3.55272
C2CD5 C2 calcium-dependent domain containing 5 -3.4737
FASTKD5 FAST kinase domains 5 -3.19288
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.13256
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.13012
LDHD lactate dehydrogenase D -2.97549
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -2.84543
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -2.69999
FOS FBJ murine osteosarcoma viral oncogene homolog -2.62604
EIF5 eukaryotic translation initiation factor 5 -2.61681
ITGB1BP1 integrin beta 1 binding protein 1 -2.4348
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -2.42336
TLR4 toll-like receptor 4 -2.1913
GNAS GNAS complex locus -2.13222
PEG10 paternally expressed 10 -2.10531