CRCGN014_HEPG2_24H:G17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-nitrosodiethanolamine 39.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN014_HEPG2_24H:G17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 4.09047
EPN2 epsin 2 3.72397
STK10 serine/threonine kinase 10 3.70482
GPATCH8 G patch domain containing 8 3.42151
PEX11A peroxisomal biogenesis factor 11 alpha 3.39439
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.27123
CCDC85B coiled-coil domain containing 85B 3.26609
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.11575
UBQLN2 ubiquilin 2 2.99262
MCOLN1 mucolipin 1 2.96761
SMIM40 small integral membrane protein 40 2.9093
DIPK1A divergent protein kinase domain 1A 2.692
KIF20A kinesin family member 20A 2.54498
ZNF589 zinc finger protein 589 2.34308
KAT7 K(lysine) acetyltransferase 7 2.09418
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.0486

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.64477
ZNF586 zinc finger protein 586 -4.74859
NGRN neugrin, neurite outgrowth associated -4.39677
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.97928
MAPK13 mitogen-activated protein kinase 13 -3.87934
GNAS GNAS complex locus -3.8755
NT5DC2 5'-nucleotidase domain containing 2 -3.81882
ADI1 acireductone dioxygenase 1 -3.8129
MRPS16 mitochondrial ribosomal protein S16 -3.80879
PCNA proliferating cell nuclear antigen -3.46838
SCAND1 SCAN domain containing 1 -3.30932
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.05415
ICAM3 intercellular adhesion molecule 3 -2.68702
KDM3A lysine (K)-specific demethylase 3A -2.61147
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.5153
CD320 CD320 molecule -2.47503
GOLT1B golgi transport 1B -2.39976
TXNRD1 thioredoxin reductase 1 -2.12196
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.07361