| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | acetohexamide 20.96 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN014_HEPG2_24H:G18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AMDHD2 | amidohydrolase domain containing 2 | 6.49247 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 5.41802 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 4.15306 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 3.72555 |
| EGF | epidermal growth factor | 3.64406 |
| PRKCD | protein kinase C, delta | 3.50518 |
| E2F2 | E2F transcription factor 2 | 3.46123 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.38565 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.24013 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.08237 |
| EPHA3 | EPH receptor A3 | 3.07565 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.06932 |
| NOSIP | nitric oxide synthase interacting protein | 2.94207 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.83088 |
| STIMATE | STIM activating enhancer | 2.81403 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.77722 |
| FZD7 | frizzled class receptor 7 | 2.7334 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.65626 |
| MAP7 | microtubule-associated protein 7 | 2.51113 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.45599 |
| PRKCH | protein kinase C, eta | 2.37374 |
| MMP1 | matrix metallopeptidase 1 | 2.31829 |
| CCNF | cyclin F | 2.19442 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 2.18234 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.1039 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 2.09875 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.07051 |
| NEK4 | NIMA-related kinase 4 | 2.03005 |
| CYCS | cytochrome c, somatic | 2.00309 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLCD3A | TLC domain containing 3A | -3.94227 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.56969 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.45979 |
| CD320 | CD320 molecule | -3.43369 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.34735 |
| LDHD | lactate dehydrogenase D | -3.2383 |
| ADI1 | acireductone dioxygenase 1 | -3.17925 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -3.15703 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -3.15069 |
| PCNA | proliferating cell nuclear antigen | -3.11536 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.07685 |
| YME1L1 | YME1-like 1 ATPase | -3.01488 |
| GNAS | GNAS complex locus | -2.96852 |
| CHMP4B | charged multivesicular body protein 4B | -2.95755 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.9483 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.94643 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -2.93766 |
| HEATR1 | HEAT repeat containing 1 | -2.93539 |
| CCNB2 | cyclin B2 | -2.87406 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.82151 |
| CCNB1 | cyclin B1 | -2.6973 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.63118 |
| ZNF586 | zinc finger protein 586 | -2.5788 |
| TES | testin LIM domain protein | -2.31942 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | -2.19897 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.16618 |
| TLR4 | toll-like receptor 4 | -2.06684 |
| MACF1 | microtubule-actin crosslinking factor 1 | -2.06277 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -2.05927 |
