| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | methylethylketoxime 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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75 genes differentially expressed following the CRCGN014_HEPG2_24H:G19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 5.57936 |
| ATP11B | ATPase, class VI, type 11B | 5.37002 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 4.13187 |
| CHMP6 | charged multivesicular body protein 6 | 4.02753 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.93943 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.90649 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.76773 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.65718 |
| NOTCH1 | notch 1 | 3.58148 |
| UBQLN2 | ubiquilin 2 | 3.53472 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.33999 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.30798 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.17947 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 3.14753 |
| GPATCH8 | G patch domain containing 8 | 2.98818 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 2.95342 |
| EPN2 | epsin 2 | 2.94189 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.765 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.72011 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.64466 |
| MELK | maternal embryonic leucine zipper kinase | 2.53897 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.52873 |
| TRIM13 | tripartite motif containing 13 | 2.4432 |
| CCNF | cyclin F | 2.41624 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.38696 |
| SLC75A1 | solute carrier family 75 member 1 | 2.32064 |
| STIMATE | STIM activating enhancer | 2.31549 |
| ZNF589 | zinc finger protein 589 | 2.2668 |
| KLHL9 | kelch-like family member 9 | 2.24938 |
| CRTAP | cartilage associated protein | 2.2242 |
| CYCS | cytochrome c, somatic | 2.20169 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.17034 |
| SNX7 | sorting nexin 7 | 2.16754 |
| ECD | ecdysoneless homolog (Drosophila) | 2.15536 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 2.12123 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.10642 |
| SLC30A9 | solute carrier family 30 (zinc transporter), member 9 | 2.10001 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.05724 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 2.03236 |
| RPA3 | replication protein A3, 14kDa | 2.02775 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP4B | charged multivesicular body protein 4B | -7.59242 |
| PCNA | proliferating cell nuclear antigen | -6.32568 |
| SPAG4 | sperm associated antigen 4 | -5.37025 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.00143 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.46988 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -4.40597 |
| ZW10 | zw10 kinetochore protein | -4.35649 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.26391 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.24201 |
| TRIB3 | tribbles pseudokinase 3 | -4.2216 |
| ADI1 | acireductone dioxygenase 1 | -4.1161 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.03705 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.9658 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.9437 |
| CDC20 | cell division cycle 20 | -3.74614 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.69202 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.63338 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.58917 |
| CCDC86 | coiled-coil domain containing 86 | -3.49697 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.4899 |
| RNF167 | ring finger protein 167 | -3.22951 |
| TLCD3A | TLC domain containing 3A | -3.2294 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -3.06978 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.88887 |
| HYOU1 | hypoxia up-regulated 1 | -2.83359 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.77268 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.7158 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.48853 |
| EGF | epidermal growth factor | -2.40401 |
| NGRN | neugrin, neurite outgrowth associated | -2.37457 |
| EFHD1 | EF-hand domain family, member D1 | -2.30842 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.17629 |
| RFPL2 | ret finger protein-like 2 | -2.10162 |
| PEG10 | paternally expressed 10 | -2.07065 |
| CCNB2 | cyclin B2 | -2.05157 |
