CRCGN014_HEPG2_24H:G22 Gene Set
Genes
60 genes differentially expressed following the CRCGN014_HEPG2_24H:G22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
5.08567
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
4.80702
|
|
MAP7
|
microtubule-associated protein 7
|
4.28638
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.78412
|
|
CCNA1
|
cyclin A1
|
3.7587
|
|
ZNF589
|
zinc finger protein 589
|
3.66934
|
|
UBQLN2
|
ubiquilin 2
|
3.55007
|
|
PLS1
|
plastin 1
|
3.43274
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.4167
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.1801
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.15823
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.12394
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
3.0117
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.9433
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.93919
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.82259
|
|
CCNF
|
cyclin F
|
2.75303
|
|
IDE
|
insulin-degrading enzyme
|
2.59952
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.57051
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
2.47814
|
|
KLHL21
|
kelch-like family member 21
|
2.40946
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.40599
|
|
RRAGA
|
Ras-related GTP binding A
|
2.23389
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.20136
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.13794
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.10447
|
|
CYCS
|
cytochrome c, somatic
|
2.02951
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-4.65799
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.79963
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.61323
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.48059
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.40331
|
|
SPAG4
|
sperm associated antigen 4
|
-3.38032
|
|
CD320
|
CD320 molecule
|
-3.2815
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.26352
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.21454
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.13384
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.02484
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.88706
|
|
DUSP6
|
dual specificity phosphatase 6
|
-2.81901
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.75345
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.74805
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.69747
|
|
CDC20
|
cell division cycle 20
|
-2.66483
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.63553
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.62215
|
|
LDHD
|
lactate dehydrogenase D
|
-2.58502
|
|
CCNB1
|
cyclin B1
|
-2.55046
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.53817
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.52401
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.51768
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.49198
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.48303
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.43767
|
|
PDZD2
|
PDZ domain containing 2
|
-2.28206
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.2787
|
|
RPS5
|
ribosomal protein S5
|
-2.17163
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.03034
|
|
GNAS
|
GNAS complex locus
|
-2.01978
|
|
CD58
|
CD58 molecule
|
-2.01324
|
