CRCGN014_HEPG2_24H:H01 Gene Set
Genes
28 genes differentially expressed following the CRCGN014_HEPG2_24H:H01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.56849
|
|
CHN1
|
chimerin 1
|
5.23284
|
|
RPL39L
|
ribosomal protein L39-like
|
4.78207
|
|
CBR3
|
carbonyl reductase 3
|
4.52481
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.01828
|
|
HOXA10
|
homeobox A10
|
3.80387
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.75818
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.37704
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.30811
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.0309
|
|
CHEK2
|
checkpoint kinase 2
|
2.79131
|
|
MAP7
|
microtubule-associated protein 7
|
2.78598
|
|
NPY
|
neuropeptide Y
|
2.60217
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.21822
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.01828
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-4.5791
|
|
ZNF586
|
zinc finger protein 586
|
-4.53908
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.52444
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.32838
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.56372
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.03375
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.86968
|
|
TLR4
|
toll-like receptor 4
|
-2.60529
|
|
PAEP
|
progestagen-associated endometrial protein
|
-2.50831
|
|
SPINK1
|
serine peptidase inhibitor, Kazal type 1
|
-2.32378
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
-2.11003
|
|
PADI3
|
peptidyl arginine deiminase, type III
|
-2.02573
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
-2.01863
|
